Photocatalytic decomposition of NO at 275 K on titanium oxides included within Y-zeolite cavities: The structure and role of the active sites

…, Y Ichihashi, M Anpo, M Hashimoto… - The Journal of …, 1996 - ACS Publications
Titanium oxide species anchored in the Y-zeolite cavities by an ion-exchange method exhibits
a high and unique photocatalytic reactivity for the direct decomposition of NO into N 2 , O …

[HTML][HTML] Metformin attenuates lung fibrosis development via NOX4 suppression

…, H Hara, T Kadota, H Yanagisawa, M Hashimoto… - Respiratory …, 2016 - Springer
Background Accumulation of profibrotic myofibroblasts in fibroblastic foci (FF) is a crucial
process for development of fibrosis during idiopathic pulmonary fibrosis (IPF) pathogenesis, …

PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis

…, K Kobayashi, H Yanagisawa, M Hashimoto… - Autophagy, 2019 - Taylor & Francis
Cigarette smoke (CS)-induced accumulation of mitochondrial damage has been widely
implicated in chronic obstructive pulmonary disease (COPD) pathogenesis. Mitophagy plays a …

Involvement of PARK2-mediated mitophagy in idiopathic pulmonary fibrosis pathogenesis

…, H Utsumi, H Yanagisawa, M Hashimoto… - The Journal of …, 2016 - journals.aai.org
Fibroblastic foci, known to be the leading edge of fibrosis development in idiopathic pulmonary
fibrosis (IPF), are composed of fibrogenic myofibroblasts. Autophagy has been implicated …

[HTML][HTML] Integrin αvβ8–expressing tumor cells evade host immunity by regulating TGF-β activation in immune cells

…, J Lou, A Elattma, S Ito, H Yanagisawa, M Hashimoto… - JCI insight, 2018 - ncbi.nlm.nih.gov
TGF-β is a promising immunotherapeutic target. It is expressed ubiquitously in a latent form
that must be activated to function. Determination of where and how latent TGF-β (L-TGF-β) is …

Azithromycin attenuates myofibroblast differentiation and lung fibrosis development through proteasomal degradation of NOX4

…, Y Fujita, H Utsumi, H Yanagisawa, M Hashimoto… - Autophagy, 2017 - Taylor & Francis
Accumulation of profibrotic myofibroblasts is involved in the process of fibrosis development
during idiopathic pulmonary fibrosis (IPF) pathogenesis. TGFB (transforming growth factor β) …

Influence of climate factors on emergency visits for childhood asthma attack

M Hashimoto, T Fukuda, T Shimizu… - Pediatrics …, 2004 - Wiley Online Library
Background : Asthma attack shows strong seasonality. The purpose of the present study was
to quantify the contribution of climate variables and other seasonal factors on the incidence …

[HTML][HTML] Pirfenidone inhibits myofibroblast differentiation and lung fibrosis development during insufficient mitophagy

…, Y Fujita, H Utsumi, H Yanagisawa, M Hashimoto… - Respiratory …, 2017 - Springer
Background Pirfenidone (PFD) is an anti-fibrotic agent used to treat idiopathic pulmonary
fibrosis (IPF), but its precise mechanism of action remains elusive. Accumulation of profibrotic …

Selective targeting of TGF-β activation to treat fibroinflammatory airway disease

…, H Yanagisawa, A Goodsell, M Hashimoto… - Science translational …, 2014 - science.org
Airway remodeling, caused by inflammation and fibrosis, is a major component of chronic
obstructive pulmonary disease (COPD) and currently has no effective treatment. Transforming …

The role of oblique subduction and strike‐slip tectonics in the evolution of Japan

A Taira, Y Saito, M Hashimoto - Geodynamics of the Western …, 1983 - Wiley Online Library
The pre‐Neogene geologic framework of Japan consists of the pre‐Jurassic terranes (older
terranes) and Jurassic to Tertiary subduction terranes, juxtaposed in a complex manner and …