Background WHO recommends Xpert MTB/RIF as initial diagnostic testing for tuberculous
meningitis. However, diagnosis remains difficult, with Xpert sensitivity of about 50–70% and …

In the USA, histoplasmosis is generally thought to occur mainly in the Ohio and Mississippi
river valleys, and the classic map of histoplasmosis distribution reflecting this is second …

Endemic mycoses such as histoplasmosis, coccidioidomycosis, blastomycosis,
paracoccidioidomycosis, and talaromycosis are well-known causes of focal and systemic disease …

Background Cryptococcus is the most common cause of adult meningitis in Africa. We assessed
the safety and microbiological efficacy of adjunctive sertraline, previously shown to have …

Tuberculous meningitis (TBM) is the most severe form of tuberculous with substantial
mortality. In May 2015, 54 researchers from 10 countries met in Da Lat, Vietnam, to discuss …

Introduction In the current time where we face a COVID-19 pandemic, there is no vaccine or
effective treatment at this time. Therefore, the prevention of COVID-19 and the rapid …

Introduction Within this large‐scale study, we compared clinical symptoms, laboratory findings,
radiographic signs, and outcomes of COVID‐19, SARS, and MERS to find unique features…

BACKGROUND: TB meningitis (TBM) diagnosis is difficult and novel diagnostic methods
are needed. The World Health Organization recommends Xpert® MTB/RIF as the initial TBM …

Meningitis remains a worldwide problem, and rapid diagnosis is essential to optimize survival.
We evaluated the utility of a multiplex PCR test in differentiating possible etiologies of …

Infectious meningitis may be due to bacterial, mycobacterial, fungal or viral agents.
Diagnosis of meningitis must take into account numerous items of patient history and …