[PDF][PDF] The incidence and risk factors of hepatocellular carcinoma in patients with nonalcoholic steatohepatitis

…, R Lopez, TAR Tamimi, AF Feldstein, NN Zein - …, 2010 - Wiley Online Library
Nonalcoholic steatohepatitis (NASH) is a well‐recognized cause of cirrhosis and has been
increasingly associated with the development of hepatocellular carcinoma (HCC). The aims …

Clinical significance of hepatitis C virus genotypes

NN Zein - Clinical microbiology reviews, 2000 - Am Soc Microbiol
On the basis of phylogenetic analysis of nucleotide sequences, multiple genotypes and
subtypes of hepatitis C virus (HCV) have been identified. Characterization of these genetic …

[PDF][PDF] In vivo assessment of liver cell apoptosis as a novel biomarker of disease severity in nonalcoholic fatty liver disease

A Wieckowska, NN Zein, LM Yerian, AR Lopez… - …, 2006 - Wiley Online Library
In patients with nonalcoholic fatty liver disease (NAFLD), a liver biopsy remains the only
reliable way to differentiate simple steatosis from nonalcoholic steatohepatitis (NASH). …

[PDF][PDF] Cytokeratin‐18 fragment levels as noninvasive biomarkers for nonalcoholic steatohepatitis: a multicenter validation study

…, A Wieckowska, AR Lopez, YC Liu, NN Zein… - …, 2009 - Wiley Online Library
Liver biopsy remains the gold standard for diagnosing nonalcoholic steatohepatitis (NASH).
We have recently demonstrated that plasma cytokeratin 18 (CK‐18) fragment levels …

Increased hepatic and circulating interleukin-6 levels in human nonalcoholic steatohepatitis

…, ZZ Li, R Lopez, NN Zein… - Official journal of the …, 2008 - journals.lww.com
BACKGROUND Nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D) are
growing public health problems, and are strongly associated. The link between the two …

Hepatitis C virus genotypes in the United States: epidemiology, pathogenicity, and response to interferon therapy

NN Zein, J Rakela, EL Krawitt, KR Reddy… - Annals of internal …, 1996 - acpjournals.org
Objective: To study 1) the geographic distribution and clinical significance of hepatitis C virus
[HCV] genotypes in the United States and 2) the influence of HCV genotypes on response …

[PDF][PDF] Three‐dimensional print of a liver for preoperative planning in living donor liver transplantation

NN Zein, IA Hanouneh, PD Bishop… - Liver …, 2013 - Wiley Online Library
The growing demand for liver transplantation and the concomitant scarcity of cadaveric livers
have increased the need for living donor liver transplantation (LDLT). Ensuring the safety of …

Treatment of eosinophilic esophagitis with inhaled corticosteroids

…, J Perrault, LJ Burgart, NN Zein… - Journal of pediatric …, 1998 - journals.lww.com
Eosinophilic esophagitis (EE) is a newly described inflammatory lesion characterized by dense
eosinophilic infiltration of the esophagus that occurs in the absence of gastroesophageal …

Role of ceramides in nonalcoholic fatty liver disease

…, T Kasumov, AJ McCullough, NN Zein… - Trends in endocrinology …, 2012 - cell.com
Nonalcoholic fatty liver disease (NAFLD) is a chronic disease with a histological spectrum
ranging from steatosis alone, to nonalcoholic steatohepatitis (NASH). The latter is associated …

Neutrophil to lymphocyte ratio: a new marker for predicting steatohepatitis and fibrosis in patients with nonalcoholic fatty liver disease

…, R Lopez, TAR Tamimi, L Yerian, NN Zein… - Liver …, 2012 - Wiley Online Library
Background Nonalcoholic steatohepatitis ( NASH ), the most severe form of nonalcoholic
fatty liver disease ( NAFLD ), is associated with inflammation and increased oxidative stress. …