Background Dupilumab (an anti-interleukin-4-receptor-α monoclonal antibody) blocks signalling
of interleukin 4 and interleukin 13, type 2/Th2 cytokines implicated in numerous allergic …

… Lucıa Quintana-Castanedo, MD,a Marta Feito-Rodrıguez, MD, PhD,a Iván Valero-López,
MD,b Clara Chiloeches-Fernández, MD,a Elena Sendagorta-Cudós, MD, PhD,a and Pedro …

Hidradenitis suppurativa (HS) is a recurrent scarring suppurative disease of the apocrine
gland-bearing areas of the body that usually affects the intertriginous areas. Prepubertal HS is …

Background Guselkumab is a drug used to treat moderate to severe plaque psoriasis.
However, real-life clinical data on its off-label use are limited, especially regarding the optimal …

Immune checkpoint inhibitors (ICI) such as anti-programmed cell death protein 1 (PD-1) or
anti-programmed death-ligand 1 (PDL-1) antibodies represent a breakthrough in the …

Malignant syphilis is a rare ulcerative variety. In the classical description of the disease, the
absence of spirochetes in tissue samples was considered as a diagnostic criterion. We report …

Background Tildrakizumab is a humanized, IgG1/κ antibody that interacts with the p19 subunit
of interleukin 23. It is approved for the treatment of moderate‐to‐severe plaque psoriasis. …

Introduction Psoriasis is a chronic disease involving the skin, which significantly impacts the
quality of life. Disease severity and treatment efficacy (ie, response) are assessed through …

Background Human monkeypox has become increasingly frequent worldwide since the
outbreak was first reported in May 2022. Objectives As cidofovir is effective against vaccinia and …

Pachyonychia congenita (PC) is a rare genodermatosis caused by a mutation in keratin
genes, which can lead to hypertrophic nail dystrophy and focal palmoplantar keratoderma (…