The complete blood cell count (CBC) is one of the most frequently ordered laboratory tests,
but some values included in the test may be overlooked. This brief review discusses 3 …

Immune-mediated thrombotic thrombocytopenic purpura is characterized by severe
thrombocytopenia and microangiopathic hemolytic anemia. It is primarily caused by immunoglobin G …

Thrombosis is a major cause of morbidity and mortality in polycythemia vera (PV) and essential
thrombocythemia (ET). The pathophysiology of thrombosis in these disorders remains …

Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is characterized by recurring
episodes of thrombotic microangiopathy, causing ischemic organ impairment. Black …

Background Cancer patients are increasingly prescribed direct oral anticoagulants (DOACs)
and targeted anticancer therapies, but limited data are available on the outcomes during …

Immune thrombotic thrombocytopenic purpura (iTTP) is primarily caused by immunoglobulin
G (IgG)–type autoantibodies that bind and inhibit plasma ADAMTS13 activity and/or …

Obstructive sleep apnea (OSA) causes intermittent hypoxia during sleep. Hypoxia predictably
initiates an increase in the blood hemoglobin concentration (Hb); yet in our analysis of 527 …

Background Coagulopathy and associated bleeding and deep vein thrombosis (DVT) are
major causes of morbidity and mortality in patients with acute leukemia. The underlying …

Hypoxia increases erythropoiesis mediated by hypoxia-inducible transcription factors (HIF),
which regulate erythropoietin transcription. Neocytolysis is a physiological mechanism that …

Allogeneic blood or marrow transplant (BMT) recipients are at risk for venous
thromboembolism (VTE) because of high-intensity therapeutic exposures, comorbidities, and a …