Innate immunity conferred by the type I interferon is critical for antiviral defense. To date only
a limited number of tripartite motif (TRIM) proteins have been implicated in modulation of …

Virus–host interactions determine an infection outcome. The Asian lineage of Zika virus (ZIKV),
responsible for the recent epidemics, has fixed a mutation in the NS1 gene after 2012 …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication and host immune
response determine coronavirus disease 2019 (COVID-19), but studies evaluating viral …

Influenza A viruses can adapt to new host species, leading to the emergence of novel
pathogenic strains. There is evidence that highly pathogenic viruses encode for non-structural 1 (…

Tripartite motif (TRIM) proteins have been implicated in multiple cellular functions, including
antiviral activity. Research efforts so far indicate that the antiviral activity of TRIMs relies, for …

An estimated 50 million dengue virus (DENV) infections occur annually and more than forty
percent of the human population is currently at risk of developing dengue fever (DF) or …

SARS-CoV-2, a novel coronavirus (CoV) that causes COVID-19, has recently emerged
causing an ongoing outbreak of viral pneumonia around the world. While distinct from SARS-CoV…

We have previously reported that mouse plasmacytoid dendritic cells (DC) produce high
levels of IL-12p70, whereas bone marrow-derived myeloid DC and splenic DC produce …

SARS-CoV-2, a novel coronavirus (CoV), has recently emerged causing an ongoing outbreak
of 2 viral pneumonia around the world. While genetically distinct from the original SARS-…

The tripartite motif containing (TRIM) proteins are a family of proteins that have been
implicated in many biological processes including cell differentiation, apoptosis, transcriptional …