▪ Objective: To prospectively study the clinical features, pathophysiology, treatment, and
prognosis of Wegener granulomatosis. ▪ Design: Of the 180 patients with Wegener …

Objective. To determine the clinical features and optimal treatment of subglottic stenosis (SGS)
in patients with Wegener's granulomatosis (WG). Methods. Review of 43 patients with …

Wegener's granulomatosis (WG) is a multisystem inflammatory disease characterized by
vasculitis, granuloma formation, and necrosis. Among 158 patients treated at the National …

BACKGROUND: The survival of patients with malignant central airway obstruction is very
limited. Although airway stenting results in significant palliation of symptoms, data regarding …

Importance Tracheal stenosis is a debilitating disorder with heterogeneity in terms of disease
characteristics and management. Repeated recurrences substantially alter patients’ quality …

Objective Ear, nose, and throat (ENT) involvement is the most prevalent manifestation of
granulomatosis with polyangiitis (Wegener's) (GPA) and correlates with permanent damage and …

Background Methods for tracheal graft research have presented persistent challenges to
investigators, and three-dimensional (3D)–printed biosynthetic grafts offer one potential …

Olfactory neuroepithelial cells (ONC) grown from biopsies of human donors are a novel cell
culture system that may facilitate studies into normal and disease-related human …

Background Reconstruction of long-segment tracheal defects can be challenging and a
suitable tracheal substitute remains lacking. We sought to create a bioengineered tracheal graft …

Background: The halogenated pyrimidines 5'-iododeoxyuridine (IdUrd) and 5'-bromodeoxyuridine
(BrdUrd) are under active study as radiation sensitizers for a variety of malignancies. …