The American Heart Association requests that this document be cited as follows: Grundy SM,
Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS, Braun LT, de Ferranti S, Faiella-…

… In parallel, an independent health data and epidemiology expert, Lee Ann Prebil, conducted a
systematic evidence review for the key topic of exercise and physical activity and conducted …

Background Non–high-density lipoprotein cholesterol (non–HDL-C) contains all known and
potential atherogenic lipid particles. Therefore, non–HDL-C level may be as good a …

Objectives : The study examined whether progression of coronary artery calcium (CAC) is a
predictor of future coronary heart disease (CHD) events. Background : CAC predicts CHD …

Background Statins are the most effective agents currently available for lowering plasma
levels of low-density lipoprotein cholesterol (LDL-C) and are the mainstay of therapy for …

Statins form the pharmacologic cornerstone of the primary and secondary prevention of
atherosclerotic cardiovascular disease. In addition to beneficial cardiovascular effects, statins …

The role of inflammation in the propagation of atherosclerosis and susceptibility to cardiovascular
(CV) events is well established. Of the wide array of inflammatory biomarkers that have …

Background: Accurate risk assessment of atherosclerotic cardiovascular disease (ASCVD)
is essential to effectively balance the risks and benefits of therapy for primary prevention. …

Background : The American College of Cardiology (ACC)/American Heart Association (AHA)
cholesterol management guidelines have significantly broadened the scope of candidates …

Background— Limited attention has been paid to negative cardiovascular disease (CVD)
risk markers despite their potential to improve medical decision making. We compared 13 …