Background Neonates and children differ from adults in physiology, pharmacologic responses
to drugs, epidemiology, and long-term consequences of thrombosis. This guideline …

Background: Despite an increase in the number of therapies available to treat patients with
immune thrombocytopenia (ITP), there are minimal data from randomized trials to assist …

Splenectomy has been a standard treatment for adult patients with idiopathic thrombocytopenic
purpura (ITP) for more than 50 years. However, the durability of responses, the ability to …

Initial management of patients with thrombotic thrombocytopenic purpura—hemolytic uremic
syndrome (TTP-HUS) is difficult because of lack of specific diagnostic criteria, high mortality …

Survival of patients with thrombotic thrombocytopenic purpura (TTP) improved dramatically
with plasma exchange treatment, revealing risk for relapse. The Oklahoma TTP Registry is a …

The recent successes of immunotherapy have shifted the paradigm in cancer treatment, but
because only a percentage of patients are responsive to immunotherapy, it is imperative to …

Reports of the incidence of ITP are few and their methodology is variable. Accurate estimates
of the incidence of immune thrombocytopenic purpura (ITP) are important to understand …

The role of parental communication and instruction concerning sexual behaviour were
studied in a community-based sample of 1083 youth aged 13–17 (mean age of 15 years; 51% …

Background Despite advances in treatment options for thrombotic thrombocytopenic purpura
(TTP), there are still limited high quality data to inform clinicians regarding its appropriate …

Background: Despite an increasing incidence of venous thromboembolism (VTE) in pediatric
patients in tertiary care settings, relatively few pediatric physicians have experience with …