[HTML][HTML] PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-κB and caspase-1-dependent cytokine processing
…, GA Manji, JM Grenier, A Al-Garawi, S Merriam… - Journal of Biological …, 2002 - ASBMB
PYRIN-containing Apaf1-like proteins (PYPAFs) are members of the nucleotide-binding site/leucine-rich
repeat (NBS/LRR) family of signal transduction proteins. We report here that …
repeat (NBS/LRR) family of signal transduction proteins. We report here that …
[HTML][HTML] CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with …
…, JL Poyet, SM Srinivasula, S Merriam… - Journal of Biological …, 2001 - ASBMB
The caspase recruitment domain (CARD) is a protein-binding module that mediates the
assembly of CARD-containing proteins into apoptosis and NF-κB signaling complexes. We …
assembly of CARD-containing proteins into apoptosis and NF-κB signaling complexes. We …
[HTML][HTML] PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-κB
…, L Wang, BJ Geddes, M Brown, S Merriam… - Journal of Biological …, 2002 - ASBMB
The PYRIN domain is a recently identified protein-protein interaction domain that is found at
the N terminus of several proteins thought to function in apoptotic and inflammatory …
the N terminus of several proteins thought to function in apoptotic and inflammatory …
[HTML][HTML] Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-κB and caspase-1
…, A Al-Garawi, R Kelly, A Carlson, S Merriam… - FEBS letters, 2002 - Elsevier
PYRIN-containing Apaf-1-like proteins (PYPAFs) are a recently identified family of proteins
thought to function in apoptotic and inflammatory signaling pathways. PYPAF1 and PYPAF7 …
thought to function in apoptotic and inflammatory signaling pathways. PYPAF1 and PYPAF7 …
[HTML][HTML] CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-κB
…, MD Jacobson, JL Poyet, S Merriam… - Journal of Biological …, 2000 - ASBMB
BCL10/CLAP is an activator of apoptosis and NF−κB signaling pathways and has been
implicated in B cell lymphomas of mucosa-associated lymphoid tissue. Although its role in …
implicated in B cell lymphomas of mucosa-associated lymphoid tissue. Although its role in …
[HTML][HTML] Card10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with BCL10 and activates NF-κB
…, X Ke, JL Poyet, GA Manji, S Merriam… - Journal of Biological …, 2001 - ASBMB
BCL10 belongs to the caspase recruitment domain (CARD) family of proteins that regulate
apoptosis and NF-κB signaling pathways. Analysis of BCL10-deficient mice has revealed that …
apoptosis and NF-κB signaling pathways. Analysis of BCL10-deficient mice has revealed that …
An innovative shared decision-making curriculum for internal medicine residents: findings from the University of Pittsburgh Medical Center
…, J Schell, S Rothenberger, S Merriam… - Academic …, 2018 - journals.lww.com
Purpose Shared decision making (SDM) is a core competency in health policy and
guidelines. Most US internal medicine residencies lack an SDM education curriculum. A …
guidelines. Most US internal medicine residencies lack an SDM education curriculum. A …
[HTML][HTML] A policy statement of the society of general internal medicine on tackling racism in medical education: reflections on the past and a call to action for the future
E Ufomata, S Merriam, A Puri, K Lupton… - Journal of general …, 2021 - Springer
Structural racism, or the practices, policies, and norms that perpetuate white supremacy, is
ubiquitous within US social systems, including in institutions of medical education. 1, 2 The …
ubiquitous within US social systems, including in institutions of medical education. 1, 2 The …
Human CARD12 is a novel CED4/Apaf-1 family member that induces apoptosis
…, M Jurman, J Cao, J Morgenstern, S Merriam… - Biochemical and …, 2001 - Elsevier
The CED4/Apaf-1 family of proteins functions as critical regulators of apoptosis and NF-κB
signaling pathways. A novel human member of this family, called CARD12, was identified that …
signaling pathways. A novel human member of this family, called CARD12, was identified that …
[HTML][HTML] Minding the gap: organizational strategies to promote gender equity in academic medicine during the COVID-19 pandemic
S Narayana, B Roy, S Merriam, E Yecies… - Journal of General …, 2020 - Springer
T he COVID-19 pandemic and its sequelae are likely to have disproportionate impact on
women physicians, professionally and personally, and we must take steps to mitigate this …
women physicians, professionally and personally, and we must take steps to mitigate this …