User profiles for Siddharth Dugar
 | Siddharth Dugar MD FCCP FCCM FASECleveland Clinic Foundation Verified email at ccf.org Cited by 959 |
[PDF][PDF] Sepsis and septic shock: Guideline-based management
Sepsis is a life-threatening organ dysfunction that results from the body’s response to infection.
It requires prompt recognition, appropriate antibiotics, careful hemodynamic support, and …
It requires prompt recognition, appropriate antibiotics, careful hemodynamic support, and …
Mavrilimumab in patients with severe COVID-19 pneumonia and systemic hyperinflammation (MASH-COVID): an investigator initiated, multicentre, double-blind …
Background In patients with COVID-19, granulocyte-macrophage colony stimulating factor (GM-CSF)
might be a mediator of the hyperactive inflammatory response associated with …
might be a mediator of the hyperactive inflammatory response associated with …
Canakinumab to reduce deterioration of cardiac and respiratory function in SARS‐CoV‐2 associated myocardial injury with heightened inflammation (canakinumab in …
Background In patients with Covid‐19, myocardial injury and increased inflammation are
associated with morbidity and mortality. We designed a proof‐of‐concept randomized …
associated with morbidity and mortality. We designed a proof‐of‐concept randomized …
[HTML][HTML] The impact of right ventricular injury on the mortality in patients with acute respiratory distress syndrome: a systematic review and meta-analysis
Background Previous studies have found various incidences of right ventricular (RV) injury
and its association with clinical outcome in patients with acute respiratory distress syndrome (…
and its association with clinical outcome in patients with acute respiratory distress syndrome (…
Assessment of symptom, disability, and financial trajectories in patients hospitalized for COVID-19 at 6 months
…, PB Doshi, IS Douglas, B Driver, SP Dugar… - JAMA network …, 2023 - jamanetwork.com
Importance Individuals who survived COVID-19 often report persistent symptoms, disabilities,
and financial consequences. However, national longitudinal estimates of symptom burden …
and financial consequences. However, national longitudinal estimates of symptom burden …
Effect of IV high-dose vitamin C on mortality in patients with sepsis: a systematic review and meta-analysis of randomized controlled trials
OBJECTIVES: The aim of this study was to conduct a systematic review and meta-analysis
of randomized controlled trials to investigate whether IV high-dose vitamin C improves the …
of randomized controlled trials to investigate whether IV high-dose vitamin C improves the …
Is left ventricular systolic dysfunction associated with increased mortality among patients with sepsis and septic shock?
… Author links open overlay panel Siddharth Dugar MD a d , Ryota Sato MD a , Sanchit Chawla
MD a , Jee Young You MD a , Xiaofeng Wang PhD b , Richard Grimm DO c , Patrick Collier …
MD a , Jee Young You MD a , Xiaofeng Wang PhD b , Richard Grimm DO c , Patrick Collier …
Acute skeletal muscle loss in SARS‐CoV‐2 infection contributes to poor clinical outcomes in COVID‐19 patients
…, A Bellar, M Biehl, S Dugar… - Journal of Cachexia …, 2022 - Wiley Online Library
Background Chronic disease causes skeletal muscle loss that contributes to morbidity and
mortality. There are limited data on the impact of dynamic muscle loss on clinical outcomes in …
mortality. There are limited data on the impact of dynamic muscle loss on clinical outcomes in …
Echocardiographic profiles and hemodynamic response after vasopressin initiation in septic shock: a cross-sectional study
Purpose Vasopressin, used as a catecholamine adjunct, is a vasoconstrictor that may be
detrimental in some hemodynamic profiles, particularly left ventricular (LV) systolic dysfunction. …
detrimental in some hemodynamic profiles, particularly left ventricular (LV) systolic dysfunction. …
Double-blind randomized proof-of-concept trial of canakinumab in patients with COVID-19 associated cardiac injury and heightened inflammation
Aims In coronavirus disease 2019 (COVID-19), myocardial injury is associated with systemic
inflammation and higher mortality. Our aim was to perform a proof of concept trial with …
inflammation and higher mortality. Our aim was to perform a proof of concept trial with …