Background Constitutive activation of KIT receptor tyrosine kinase is critical in the pathogenesis
of gastrointestinal stromal tumors. Imatinib mesylate, a selective tyrosine kinase inhibitor, …

ContextVertebral fractures significantly increase lifetime risk of future fractures, but risk of
further vertebral fractures in the period immediately following a vertebral fracture has not been …

ONJ has been increasingly suspected to be a potential complication of bisphosphonate
therapy in recent years. Thus, the ASBMR leadership appointed a multidisciplinary task force to …

PURPOSE: We conducted a 5-year, double-blind, randomized, placebo-controlled study to
determine whether salmon calcitonin nasal spray reduced the risk of new vertebral fractures …

In this tutorial article, the concepts of correlation and regression are reviewed and demonstrated.
The authors review and compare two correlation coefficients, the Pearson correlation …

The field of interventional oncology with use of image-guided tumor ablation requires
standardization of terminology and reporting criteria to facilitate effective communication of ideas …

The International Osteoporosis Foundation (IOF) and the International Federation of Clinical
Chemistry and Laboratory Medicine (IFCC) recommend that a marker of bone formation (…

As multidetector CT has come to play a more central role in medical care and as CT image
quality has improved, there has been an increase in the frequency of detecting “incidental …

OBJECTIVE To characterize the relationships between adherence (compliance and persistence)
to bisphosphonate therapy and risk of specific fracture types in postmenopausal women…

Objectives Existing practice guidelines for osteoarthritis (OA) analyze the evidence behind
each proposed treatment but do not prioritize the interventions in a given sequence. The …