User profiles for Suneel Kamath
 | Suneel Kamath, MDAssistance Professor of Medicine, Cleveland Clinic Lerner College of Medicine Verified email at ccf.org Cited by 938 |
[HTML][HTML] RLY-4008, the First Highly Selective FGFR2 Inhibitor with Activity across FGFR2 Alterations and Resistance Mutations
Patients with FGFR2 -driven cancers derive limited benefit from pan-FGFRi due to multiple
FGFR1–4-mediated toxicities and acquired FGFR2 resistance mutations. RLY-4008 is a …
FGFR1–4-mediated toxicities and acquired FGFR2 resistance mutations. RLY-4008 is a …
[PDF][PDF] A multi-band spectral subtraction method for enhancing speech corrupted by colored noise.
S Kamath, P Loizou - ICASSP, 2002 - Citeseer
The spectral subtraction method is a well-known noise reduction technique. Most
implementations and variations of the basic technique advocate subtraction of the noise spectrum …
implementations and variations of the basic technique advocate subtraction of the noise spectrum …
Ipilimumab and gemcitabine for advanced pancreatic cancer: a phase Ib study
SD Kamath, A Kalyan, S Kircher, H Nimeiri… - The …, 2020 - academic.oup.com
… Suneel D. Kamath … Correspondence: Suneel Kamath, MD, Division of Hematology and
Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, 676 N. …
Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, 676 N. …
Long-term gemcitabine treatment reshapes the pancreatic tumor microenvironment and sensitizes murine carcinoma to combination immunotherapy
These data suggest that long-term treatment with gemcitabine leads to extensive
reprogramming of the pancreatic tumor microenvironment and that patients who progress on …
reprogramming of the pancreatic tumor microenvironment and that patients who progress on …
[HTML][HTML] Immune checkpoint inhibitors for the treatment of central nervous system (CNS) metastatic disease
SD Kamath, PU Kumthekar - Frontiers in oncology, 2018 - frontiersin.org
While the CNS has long been viewed as an immune-privileged environment, a paradigm shift
in neuro-immunology has elevated the role of systemic immunotherapy for the treatment of …
in neuro-immunology has elevated the role of systemic immunotherapy for the treatment of …
Automatic virtual machine configuration for database workloads
…, K Salem, P Kokosielis, S Kamath - ACM Transactions on …, 2008 - dl.acm.org
Virtual machine monitors are becoming popular tools for the deployment of database
management systems and other enterprise software. In this article, we consider a common …
management systems and other enterprise software. In this article, we consider a common …
The immune modifying effects of chemotherapy and advances in chemo-immunotherapy
DR Principe, SD Kamath, M Korc, HG Munshi - Pharmacology & …, 2022 - Elsevier
Immune checkpoint inhibitors (ICIs) have transformed the treatment paradigm for several
malignancies. While the use of single-agent or combined ICIs has achieved acceptable …
malignancies. While the use of single-agent or combined ICIs has achieved acceptable …
DPYD Testing: Time to Put Patient Safety First
In 2018, a patient received capecitabine without prior testing for dihydropyrimidine dehydrogenase
(DPYD) and later presented with vomiting, rash, and diarrhea. The hospital failed to …
(DPYD) and later presented with vomiting, rash, and diarrhea. The hospital failed to …
Trials and tribulations of pancreatic cancer immunotherapy
Immunotherapy has revolutionized cancer treatment in the last decade, and strategies to re-activate
cytotoxic immunity are now standard of care in several malignancies. Despite rapid …
cytotoxic immunity are now standard of care in several malignancies. Despite rapid …
[HTML][HTML] FGFR3–TACC3: a novel gene fusion in cervical cancer
Cervical cancer epitomizes the success of cancer prevention through the human papillomavirus
(HPV) vaccine, but significant challenges remain in the treatment of advanced disease. …
(HPV) vaccine, but significant challenges remain in the treatment of advanced disease. …