[HTML][HTML] ABT-450/r–ombitasvir and dasabuvir with or without ribavirin for HCV

…, BR Bhandari, FA Caruntu, T Sepe… - … England Journal of …, 2014 - Mass Medical Soc
Background The interferon-free regimen of ABT-450 with ritonavir (ABT-450/r), ombitasvir,
and dasabuvir with or without ribavirin has shown efficacy in inducing a sustained virologic …

[HTML][HTML] Effects of belapectin, an inhibitor of galectin-3, in patients with nonalcoholic steatohepatitis with cirrhosis and portal hypertension

…, M Rodriguez, R Rubin, M Ryan, A Scanga, T Sepe… - Gastroenterology, 2020 - Elsevier
Background & Aims Increased levels of galectin 3 have been associated with nonalcoholic
steatohepatitis (NASH) and contribute to toxin-induced liver fibrosis in mice. GR-MD-02 (…

Bacterial overgrowth without clinical malabsorption in elderly hypochlorhydric subjects

JR Saltzman, KV Kowdley, MC Pedrosa, T Sepe… - Gastroenterology, 1994 - Elsevier
Background/Aims: Bacterial overgrowth of the small intestine commonly occurs in association
with hypochlorhydria caused by atrophic gastritis or during treatment with omeprazole. The …

Fixed-dose combination therapy with daclatasvir, asunaprevir, and beclabuvir for noncirrhotic patients with HCV genotype 1 infection

…, L Mollison, M Bennett, E Tse, N Bräu, J Levin, T Sepe… - Jama, 2015 - jamanetwork.com
… Dr Sepe reported having received grants and personal fees from and having served on a
speakers’ bureau for Gilead and AbbVie. Dr Lee reported having received grants and personal …

Deferred treatment with sofosbuvir–velpatasvir–voxilaprevir for patients with chronic hepatitis C virus who were previously treated with an NS5A inhibitor: An open …

…, L Serfaty, AJ Thompson, TE Sepe… - The lancet …, 2018 - thelancet.com
Background Direct-acting antiviral regimens containing NS5A inhibitors are highly effective
treatments for chronic hepatitis C virus (HCV) infection, but are not always successful. In the …

[HTML][HTML] Giant duodenal ulcers

EB Newton, MR Versland, TE Sepe - World Journal of …, 2008 - ncbi.nlm.nih.gov
Giant duodenal ulcers (GDUs) are a subset of duodenal ulcers that have historically
resulted in greater morbidity than usual duodenal ulcers. Until recently, few cases had been …

Interaction between vitamin K nutriture and bacterial overgrowth in hypochlorhydria induced by omeprazole

SAR Paiva, TE Sepe, SL Booth, ME Camilo… - The American journal of …, 1998 - Elsevier
Subjects taking a hydrogen pump blocking agent (omeprazole) develop bacterial overgrowth
of the small intestine. We tested the hypothesis that this bacterial overgrowth produces …

Balapiravir plus peginterferon alfa-2a (40KD)/ribavirin in a randomized trial of hepatitis C genotype 1 patients

…, L Rossaro, VK Rustgi, T Sepe… - Annals of …, 2012 - medigraphic.com
Introduction. Balapiravir (R1626, RG1626) is the prodrug of a nucleoside analogue inhibitor
of the hepatitis C virus (HCV) RNA-dependent RNA polymerase (R1479, RG1479). This …

Liver enzymes: No trivial elevations, even if asymptomatic.

B Agganis, D Lee, T Sepe - Cleveland Clinic Journal of Medicine, 2018 - europepmc.org
Primary care physicians are at the forefront in screening for abnormal levels of liver enzymes
and investigating the likely causes by obtaining a detailed history and physical examination…

[HTML][HTML] Advancing research, awareness, screening, and linkage to care to eliminate HDV in the US

…, A Southworth, D Dieterich, T Sepe - Hepatology …, 2023 - journals.lww.com
HDV, which coinfects individuals living with HBV, is the most aggressive form of viral hepatitis.
Compared with hepatitis B monoinfection, hepatitis delta is associated with more rapid …