Background: Cardiac sarcomas are rare and have a poor prognosis. The median overall
survival remains dismal and has been reported ranging from 6 months to a few years. Primary …

Cutaneous lymphoid hyperplasia (CLH) has been proposed to be the benign end of a continuum
of lymphoproliferative disorders with cutaneous lymphoma at its malignant extreme. An …

Purpose: In the setting of target-based anticancer drug development, it is critical to establish
that the observed preclinical activity can be attributed to modulation of the intended target in …

. ABSTRACT Immune thrombocytopenia (ITP) in adults is a chronic disease resulting from
increased platelet destruction and impaired platelet production. Splenectomy remains the …

Temozolomide (TMZ) is a methylating agent of the imidotetrazine class, whose cytotoxic
product is O 6 -methylguanine DNA adducts, which initiate a futile recycling of the mismatch …

Early phase evaluation of anticancer drugs has traditionally used toxicity (usually hematological)
rather than efficacy end points to establish appropriate dosing schedules. To establish …

Small-cell carcinoma of the urinary bladder is a rare and aggressive type of bladder cancer
that has a poor prognosis. The incidence has been gradually increasing because of the …

Metaplastic Breast Cancer: Characteristics and Survival Outcomes Page 1 Review began 08/21/2022
Review ended 08/26/2022 Published 08/29/2022 © Copyright 2022 Thapa et al. This is an …

Lung cancer is considered the number one killer among all cancers. Recent observations
have altered the treatment paradigm for non-small-cell lung cancer (NSCLC). The discovery of …

Purpose: In non-Hodgkin lymphomas (NHLs), the bone marrow (BM) involvement is a sign
of extensive disease and the iliac crest BM biopsy (BMB) is the established method for the …