User profiles for Ulf Knoblich
Ulf KnoblichScientist II, Allen Institute for Brain Science Verified email at alleninstitute.org Cited by 6961 |
Driving fast-spiking cells induces gamma rhythm and controls sensory responses
Cortical gamma oscillations (20-80 Hz) predict increases in focused attention, and failure in
gamma regulation is a hallmark of neurological and psychiatric disease. Current theory …
gamma regulation is a hallmark of neurological and psychiatric disease. Current theory …
[PDF][PDF] Arousal and locomotion make distinct contributions to cortical activity patterns and visual encoding
Spontaneous and sensory-evoked cortical activity is highly state-dependent, yet relatively little
is known about transitions between distinct waking states. Patterns of activity in mouse V1 …
is known about transitions between distinct waking states. Patterns of activity in mouse V1 …
Targeted optogenetic stimulation and recording of neurons in vivo using cell-type-specific expression of Channelrhodopsin-2
A major long-term goal of systems neuroscience is to identify the different roles of neural
subtypes in brain circuit function. The ability to causally manipulate selective cell types is critical …
subtypes in brain circuit function. The ability to causally manipulate selective cell types is critical …
[PDF][PDF] A suite of transgenic driver and reporter mouse lines with enhanced brain-cell-type targeting and functionality
Modern genetic approaches are powerful in providing access to diverse cell types in the brain
and facilitating the study of their function. Here, we report a large set of driver and reporter …
and facilitating the study of their function. Here, we report a large set of driver and reporter …
A theory of object recognition: computations and circuits in the feedforward path of the ventral stream in primate visual cortex
We describe a quantitative theory to account for the computations performed by the feedforward
path of the ventral stream of visual cortex and the local circuits implementing them. We …
path of the ventral stream of visual cortex and the local circuits implementing them. We …
A quantitative theory of immediate visual recognition
Human and non-human primates excel at visual recognition tasks. The primate visual system
exhibits a strong degree of selectivity while at the same time being robust to changes in the …
exhibits a strong degree of selectivity while at the same time being robust to changes in the …
Mapping brain networks in awake mice using combined optical neural control and fMRI
Behaviors and brain disorders involve neural circuits that are widely distributed in the brain.
The ability to map the functional connectivity of distributed circuits, and to assess how this …
The ability to map the functional connectivity of distributed circuits, and to assess how this …
A large-scale standardized physiological survey reveals functional organization of the mouse visual cortex
To understand how the brain processes sensory information to guide behavior, we must know
how stimulus representations are transformed throughout the visual cortex. Here we report …
how stimulus representations are transformed throughout the visual cortex. Here we report …
[HTML][HTML] Relationship between simultaneously recorded spiking activity and fluorescence signal in GCaMP6 transgenic mice
Fluorescent calcium indicators are often used to investigate neural dynamics, but the relationship
between fluorescence and action potentials (APs) remains unclear. Most APs can be …
between fluorescence and action potentials (APs) remains unclear. Most APs can be …
Characterization of the functional MRI response temporal linearity via optical control of neocortical pyramidal neurons
The blood oxygenation level-dependent (BOLD) signal serves as the basis for human
functional MRI (fMRI). Knowledge of the properties of the BOLD signal, such as how linear its …
functional MRI (fMRI). Knowledge of the properties of the BOLD signal, such as how linear its …