Di(n-butyl) phthalate (DBP) is a commercially important plasticizer and ubiquitous environmental
contaminant. Since previous, limited dose-response studies with DBP that reported …

Sleep in depressed patients resembles sleep in normal subjects whose circadian rhythms of
temperature and rapid-eye-movement sleep are phase-advanced (shifted earlier) relative to …

Adult male rats previously exposed on gestation days (GD) 12–21 to di(n-butyl) phthalate (DBP)
have reproductive tract malformations, particularly agenesis of the epididymis, …

Background In animals, the circadian pacemaker regulates seasonal changes in behavior
by transmitting a signal of day length to other sites in the organism. The signal is expressed …

Di(n-butyl) phthalate (DBP) alters male reproductive development by decreasing testicular
testosterone (T) production when fetuses are exposed on gestation days (GD) 12–21. …

• Data from all-night EEG sleep studies were used to distinguish normal subjects, primary
depressed patients, and primary insomniac patients. In part 1, we compared 41 normal subjects…

The N-methyl-d-aspartate (NMDA) receptor antagonist ketamine has rapid antidepressant
effects in treatment-resistant major depressive disorder (MDD). In rats, ketamine selectively …

All-night electroencephalographic (EEG) sleep data were examined as a function of age in
normal control subjects and hospitalized, unmedicated depressed patients with primary …

The Smith-Magenis syndrome is a rare, complex multisystemic disorder featuring, mental
retardation and multiple congenital anomalies caused by a heterozygous interstitial deletion of …

BACKGROUND: Melanopsin, a non-visual photopigment, may play a role in aberrant
responses to low winter light levels in Seasonal Affective Disorder (SAD). We hypothesize that …