More articles from Current Drug Therapy
- Efficacy of beta blockade, thrombolytic therapy, and coronary angioplasty in diabetic patients with coronary artery disease
Determining the effectiveness of these interventions in diabetic patients has received little attention, despite the association of diabetes with increased mortality from coronary artery disease.
- Current hypertension management: separating fact from fiction
Speculations that have led many physicians to abandon the use of diuretics have not proven to be of clinical relevance in most instances.
- Nontraditional combination pharmacotherapy of hypertension
Which new combinations hold the most promise for safer, more effective blood pressure control ?
- Adrenergic agents: clinical trials and experiences
Different beta blockers have different effects on cardiac output and heart rate, and some may diminish detrimental arterial changes induced by hypertension. A long-term preventive effect against coronary artery disease remains to be demonstrated.
- The hemodynamic effects of adrenergic blocking agents
Alpha-1 blockers may suit patients with active life-styles, peripheral vascular disorders, or high blood-cholesterol levels, while beta blockers are useful in tachycardia, palpitations, or angina pectoris. An overview of the pharmacologic qualities and numerous clinical applications of these agents.
- Moricizine: pharmacodynamic, pharmacokinetic, and therapeutic profile of a new antiarrhythmic
This agent appears to be well tolerated, with a low incidence of both short-term and long-term side effects. However, more clinical experience is needed to better define its antiarrhythmic role.