More articles from Current Drug Therapy
- Current hypertension management: separating fact from fiction
Speculations that have led many physicians to abandon the use of diuretics have not proven to be of clinical relevance in most instances.
- Nontraditional combination pharmacotherapy of hypertension
Which new combinations hold the most promise for safer, more effective blood pressure control ?
- Adrenergic agents: clinical trials and experiences
Different beta blockers have different effects on cardiac output and heart rate, and some may diminish detrimental arterial changes induced by hypertension. A long-term preventive effect against coronary artery disease remains to be demonstrated.
- The hemodynamic effects of adrenergic blocking agents
Alpha-1 blockers may suit patients with active life-styles, peripheral vascular disorders, or high blood-cholesterol levels, while beta blockers are useful in tachycardia, palpitations, or angina pectoris. An overview of the pharmacologic qualities and numerous clinical applications of these agents.
- Moricizine: pharmacodynamic, pharmacokinetic, and therapeutic profile of a new antiarrhythmic
This agent appears to be well tolerated, with a low incidence of both short-term and long-term side effects. However, more clinical experience is needed to better define its antiarrhythmic role.
- Omeprazole: a new drug for the treatment of acid^peptic diseases
Gastroesophageal reflux disease, Zollinger-Ellison syndrome, duodenal ulcer, and gastric ulcer are among the disorders that have responded to treatment with this agent—the first of a new class of gastric antisecretory drugs.