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Cleveland Clinic Journal of Medicine

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    Who would have thought?
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine April 2007, 74 (4) 247;

    Fifteen years ago, universal screening for human immunodeficiency virus would have been met with cries of discrimination and therapeutic nihilism, but not in 2007. Who would have thought?

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    Recognizing a common disease hiding in plain sight
    Brian F. Mandell, MD, PhD
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    Clinicians often fail to diagnose celiac disease promptly. They don’t realize how common it is, and they don’t recognize its many manifestations other than diarrhea.

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    Guy M. Chisolm, PhD
    Cleveland Clinic Journal of Medicine March 2007, 74 (3 suppl 2) S3-S5;
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    What to do with a broken heart
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine February 2007, 74 (2) 87;

    This issue contains papers discussing noninvasive cardiac testing, the controversy surrounding late thrombosis associated with drug-eluting stents, and how to recognize and repair an atrial septal defect or patent foramen ovale.

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    Why effective drugs don’t work for everyone
    Brian F. Mandell, MD, PhD
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    For now, the concept of antiplatelet resistance is useful and probably biologically relevant, but it isn’t ready to be incorporated into our clinical practice.

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    The uric acid hypothesis: Out with the old, in with the … old
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine December 2006, 73 (12) 1038;

    The death knell for the idea that serum urate mediates cardiovascular disease tolled about 25 years ago. But now the concept is being revived.

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    The surgical unsupersizing of America
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine November 2006, 73 (11) 960;

    For years, “fat surgery” was viewed with skepticism by many internists. The tide is turning, but there is still no free lunch.

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    Oil it where it squeaks: Evidence, experience, and osteoarthritis therapy
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine October 2006, 73 (10) 880;

    Since many patients with osteoarthritis do experience relief with intra-articular therapy, it may indeed pay to “oil it where it squeaks.” I just wonder how much it matters what oil we use.

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    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine September 2006, 73 (9) 784;

    At ccjm.org you can find all of our articles, free CME credit, and now the proceedings of the second annual Cleveland Clinic Perioperative Medicine Summit.

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    Treating cardiovascular disease by treating inflammation: From magic bullets to smart bombs
    Brian F. Mandell, MD, PhD
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    Statins seem to do it all. Originally thought to be magic bullets that lower cholesterol, they are now known to be smart bombs that also decrease C-reactive protein.

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