More articles from From the editor
- Another vaccine article? Yes, but a different vaccine
As newer vaccines against Streptococcus pneumoniae have arrived, so have confusing recommendations and guidelines for the sequence and timing of administration.
- Decongesting heart failure with diuretics: Easier to prescribe than to fully understand
Digging deep into the pathophysiology of diuretic resistance reveals complex interacting pathways. But none of these pathways can fully explain or be used to safely reverse diuretic resistance.
- Balancing the myths of corticosteroid therapy
No class of drug has more mythical attributes, interfaces with different medical specialties, or clinical street lore than corticosteroids.
- Circulating lipids are not all bad: An LDL mimic that may be only skin deep
Although lipoprotein-X separates out by density in the low-density lipoprotein (LDL) fraction and thus may appear as LDL in the laboratory report, it is biologically unique.
- Nontuberculous mycobacterial musculoskeletal infections: Recognizable, when suspected
Two articles in this issue offer valuable insight into when to suspect these infections in patients who present with swollen, indurated, peripheral soft-tissue structures.
- A clinical trial and another clinical practice bites the dust, or should there not be an appendix?
Studies over the past 2 decades have assessed an alternative approach to acute appendicitis: treatment with systemic antibiotics and observation.
- There should be more GOLD in the EMR
We can do better at making the clinical note a useful tool for communication in the electronic medical record.
- Treating anemia: It’s not just the EPO
Long-term effects of treatment with the new oral inhibitors of prolyl hydroxylase will need to be carefully monitored, as prolyl hydroxylase is a key structural component of diverse proteins.
- Potential systemic benefits of shocking or blocking nerves
What has really caught my attention is the expanding research on controlled regional neuromodulation and its impact on systemic physiology and inflammation.
- Anaphylaxis: Expanding our perspective
Anaphylaxis is not always the extreme scenario we learned about in medical school. There is a range of far milder allergic infusion reactions that are nonetheless anaphylaxis.