More articles from Personalizing Patient Care

  • How to spot heritable breast cancer: A primary care physician’s guide

    Marissa Smith, MS, CGC, Jessica Mester, MS, CGC and Charis Eng, MD, PhD
    • Cleveland Clinic Journal of Medicine January 2014, 81 (1) 31-40;
    • DOI: https://doi.org/10.3949/ccjm.81a.13051

    • Because breast cancer is common, primary care physicians will encounter many patients who have a personal or family history of it. Many patients may benefit from referral to a cancer genetics program for assessment, genetic counseling, and consideration of genetic testing. This article discusses the complexities of risk assessment in cancer genetics (focusing on breast cancer), and highlights the primary care physician’s role in identifying and caring for patients at risk.

  • Clinical applications of pharmacogenetics: Present and near future

    Patrick A. Gladding, MBChB, PhD
    • Cleveland Clinic Journal of Medicine August 2013, 80 (8) 477-482;
    • DOI: https://doi.org/10.3949/ccjm.80a.12111

    • Pharmacogenetics promises to give clinicians the tools to make treatment decisions based on genetic testing.

  • Should we use pharmacogenetic testing when prescribing warfarin?

    Mary Rouse, MPH, Cari Cristiani, PharmD and Kathryn A. Teng, MD
    • Cleveland Clinic Journal of Medicine August 2013, 80 (8) 483-486;
    • DOI: https://doi.org/10.3949/ccjm.80a.12184

    • There is evidence in favor of testing, but not yet enough to strongly recommend it.

  • TOC Icon

    A 67-year old man with an abdominal aortic aneurysm

    Allison LaBoon, MD and Tara Marie Mastracci, MD, MSc, FRCSC
    • Cleveland Clinic Journal of Medicine March 2013, 80 (3) 161-167;
    • DOI: https://doi.org/10.3949/ccjm.80a.12156

    • Who should be screened, what is the benefit, and how should patients found to have an aneurysm be treated?

  • Detecting and managing hereditary colorectal cancer syndromes in your practice

    Brandie Heald, MS, CGC, James Church, MBChB, FRACS, Thomas Plesec, MD and Carol A. Burke, MD, FACG, FACP, FASGE
    • Cleveland Clinic Journal of Medicine November 2012, 79 (11) 787-796;
    • DOI: https://doi.org/10.3949/ccjm.79a.11165

    • These patients need to be identified so that they and their families can receive genetic counseling and testing and risk-reducing treatment.

  • Genetic counselors: Your partners in clinical practice

    Jessica L. Mester, MS, CGC, Allison H. Schreiber, MS, CGC and Rocio T. Moran, MD
    • Cleveland Clinic Journal of Medicine August 2012, 79 (8) 560-568;
    • DOI: https://doi.org/10.3949/ccjm.79a.11091

    • As our understanding of the human genome has grown, so too has the need for health care providers to help patients and families understand the implications of these discoveries.

  • TOC Icon

    Family history: Still relevant in the genomics era

    Megan Doerr, MS, CGC and Kathryn Teng, MD, FACP
    • Cleveland Clinic Journal of Medicine May 2012, 79 (5) 331-336;
    • DOI: https://doi.org/10.3949/ccjm.79a.11065

    • Family history is still relevant, being a proxy for genetic, environmental, and behavioral risks to health.