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Cleveland Clinic Journal of Medicine

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    How to spot heritable breast cancer: A primary care physician’s guide
    Marissa Smith, MS, CGC, Jessica Mester, MS, CGC and Charis Eng, MD, PhD
    Cleveland Clinic Journal of Medicine January 2014, 81 (1) 31-40; DOI: https://doi.org/10.3949/ccjm.81a.13051

    Because breast cancer is common, primary care physicians will encounter many patients who have a personal or family history of it. Many patients may benefit from referral to a cancer genetics program for assessment, genetic counseling, and consideration of genetic testing. This article discusses the complexities of risk assessment in cancer genetics (focusing on breast cancer), and highlights the primary care physician’s role in identifying and caring for patients at risk.

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    Clinical applications of pharmacogenetics: Present and near future
    Patrick A. Gladding, MBChB, PhD
    Cleveland Clinic Journal of Medicine August 2013, 80 (8) 477-482; DOI: https://doi.org/10.3949/ccjm.80a.12111

    Pharmacogenetics promises to give clinicians the tools to make treatment decisions based on genetic testing.

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    Should we use pharmacogenetic testing when prescribing warfarin?
    Mary Rouse, MPH, Cari Cristiani, PharmD and Kathryn A. Teng, MD
    Cleveland Clinic Journal of Medicine August 2013, 80 (8) 483-486; DOI: https://doi.org/10.3949/ccjm.80a.12184

    There is evidence in favor of testing, but not yet enough to strongly recommend it.

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    A 67-year old man with an abdominal aortic aneurysm
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    Cleveland Clinic Journal of Medicine March 2013, 80 (3) 161-167; DOI: https://doi.org/10.3949/ccjm.80a.12156

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    Detecting and managing hereditary colorectal cancer syndromes in your practice
    Brandie Heald, MS, CGC, James Church, MBChB, FRACS, Thomas Plesec, MD and Carol A. Burke, MD, FACG, FACP, FASGE
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    These patients need to be identified so that they and their families can receive genetic counseling and testing and risk-reducing treatment.

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    Genetic counselors: Your partners in clinical practice
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    Cleveland Clinic Journal of Medicine August 2012, 79 (8) 560-568; DOI: https://doi.org/10.3949/ccjm.79a.11091

    As our understanding of the human genome has grown, so too has the need for health care providers to help patients and families understand the implications of these discoveries.

  • Family history: Still relevant in the genomics era
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    Family history: Still relevant in the genomics era
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    Family history is still relevant, being a proxy for genetic, environmental, and behavioral risks to health.

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