More articles from Review

  • Anticoagulation and antiplatelet therapy in acute coronary syndromes
    Anticoagulation and antiplatelet therapy in acute coronary syndromes
    Dhssraj Singh, MD, Kamal Gupta, MD and James L. Vacek, MD, MSc
    Cleveland Clinic Journal of Medicine February 2014, 81 (2) 103-114; DOI: https://doi.org/10.3949/ccjm.81a.13016

    Antiplatelet and anticoagulant drugs prevent ischemic events but can cause bleeding. Here is how to optimize the benefit.

  • Clinical update in sexually transmitted diseases –2014
    Robyn Neblett Fanfair, MD, MPH and Kimberly A. Workowski, MD
    Cleveland Clinic Journal of Medicine February 2014, 81 (2) 91-101; DOI: https://doi.org/10.3949/ccjm.81a.13090

    With recent changes to the health care landscape, expect to encounter more patients with STDs.

  • Managing risks of TNF inhibitors: An update for the internist
    Jennifer Hadam, MD, Elie Aoun, MD, MS, Kofi Clarke, MD and Mary Chester Wasko, MD, MSc
    Cleveland Clinic Journal of Medicine February 2014, 81 (2) 115-127; DOI: https://doi.org/10.3949/ccjm.81a.12121

    Tumor necrosis factor inhibitors pose infrequent but serious risks, including infection and malignancy.

  • Obesity in the elderly: More complicated than you think
    Derrick C. Cetin, DO and Gaelle Nasr, BA
    Cleveland Clinic Journal of Medicine January 2014, 81 (1) 51-61; DOI: https://doi.org/10.3949/ccjm.81a.12165

    The number of obese older adults is on the rise, although we lack a proper definition of obesity in this age group. The ambiguity is primarily related to sarcopenia, the progressive loss of muscle and gain in fat that come with aging. Whether to treat and how to treat obesity in the elderly is controversial because of a paucity of established guidelines, but also because of the obesity paradox—ie, the apparently protective effect of obesity in this age group.

  • Albuminuria: When urine predicts kidney and cardiovascular disease
    Reejis Stephen, MD, SM, Stacey E. Jolly, MD, MAS, Joseph V. Nally, MD and Sankar D. Navaneethan, MD, MPH
    Cleveland Clinic Journal of Medicine January 2014, 81 (1) 41-50; DOI: https://doi.org/10.3949/ccjm.81a.13040

    Albuminuria is common. Traditionally considered a precursor to diabetic nephropathy, it has now been directly linked to adverse cardiovascular outcomes and death, independent of other risk factors. In this review, we compare the measures of albuminuria, examine the evidence linking it to renal failure, cardiovascular disease, and death, and provide recommendations for its testing and management.

  • Antiplatelet therapy to prevent recurrent stroke: Three good options
    Antiplatelet therapy to prevent recurrent stroke: Three good options
    Atizazul H. Mansoor, MD, Mohammad T. Mujtaba, MD and Brian Silver, MD
    Cleveland Clinic Journal of Medicine December 2013, 80 (12) 787-795; DOI: https://doi.org/10.3949/ccjm.80a.12149

    Aspirin, dipyridamole, and clopidogrel are important parts of therapy to prevent recurrent stroke of atherosclerotic origin.

  • Third universal definition of myocardial infarction: Update, caveats, differential diagnoses
    David M. Tehrani, MS and Arnold H. Seto, MD, MPA
    Cleveland Clinic Journal of Medicine December 2013, 80 (12) 777-786; DOI: https://doi.org/10.3949/ccjm.80a.12158

    Troponin levels are elevated in nearly everyone having a myocardial infarction—but also in many who are not. Hence, clinical judgment is needed.

  • Myasthenia gravis: Newer therapies offer sustained improvement
    Myasthenia gravis: Newer therapies offer sustained improvement
    Yuebing Li, MD, PhD, Yeeshu Arora, MD and Kerry Levin, MD
    Cleveland Clinic Journal of Medicine November 2013, 80 (11) 711-721; DOI: https://doi.org/10.3949/ccjm.80a.13044

    The prognosis has dramatically improved; the death rate used to be 75%, now it is 4.5%.

  • Sleep disturbances in cancer patients: Underrecognized and undertreated
    Saurabh Dahiya, MD, Manmeet S. Ahluwalia, MD and Harneet K. Walia, MD
    Cleveland Clinic Journal of Medicine November 2013, 80 (11) 722-732; DOI: https://doi.org/10.3949/ccjm.80a.12170

    In cancer patients, sleep disturbances are a treatable problem that profoundly affect all aspects of quality of life.

  • Hepatocellular carcinoma: Options for diagnosing and managing a deadly disease
    Arvind R. Murali, MD, Carlos Romero-Marrero, MD, Federico Aucejo, MD and K.V. Narayanan Menon, MD
    Cleveland Clinic Journal of Medicine October 2013, 80 (10) 645-653; DOI: https://doi.org/10.3949/ccjm.80a.12163

    Because early diagnosis improves the chances of survival, it is important to identify patients who would benefit from surveillance.

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