Latest Articles

  • E-cigarettes: Safe to recommend to patients?
    Jason M. Jerry, MD, FAPA, Gregory B. Collins, MD, DFAPA and David Streem, MD
    Cleveland Clinic Journal of Medicine August 2015, 82 (8) 521-526; DOI: https://doi.org/10.3949/ccjm.82a.14054

    E-cigarettes have never been subjected to testing of safety or efficacy as nicotine replacement therapy.

  • Electrocardiographic changes in amitriptyline overdose
    Farayi Mbuvah, MD, Frunze Petrosyan, MD, Nirosshan Thiruchelvam, MD and Gaurav Kistangari, MD
    Cleveland Clinic Journal of Medicine July 2015, 82 (7) 396-398; DOI: https://doi.org/10.3949/ccjm.82a.13135

    A 49-year-old woman was unresponsive after taking an unknown quantity of amitriptyline.

  • Umbilical hernia in a patient with cirrhosis
    Pieter Martens, MD and Wim Laleman, MD, PhD
    Cleveland Clinic Journal of Medicine July 2015, 82 (7) 404-405; DOI: https://doi.org/10.3949/ccjm.82a.14012

    Ascites is the major predisposing factor, since it causes muscle wasting and increases intra-abdominal pressure.

  • Should thiopurine methyltransferase (TPMT) activity be determined before prescribing azathioprine, mercaptopurine, or thioguanine?
    Jennifer DiPiero, MEd, Kathryn Teng, MD and J. Kevin Hicks, PharmD, PhD
    Cleveland Clinic Journal of Medicine July 2015, 82 (7) 409-413; DOI: https://doi.org/10.3949/ccjm.82a.14106

    Testing can identify patients at risk of life-threatening myelosuppression on these drugs.

  • Ceftaroline fosamil: A super-cephalosporin?
    Riane J. Ghamrawi, PharmD, BCPS, Elizabeth Neuner, PharmD and Susan J. Rehm, MD
    Cleveland Clinic Journal of Medicine July 2015, 82 (7) 437-444; DOI: https://doi.org/10.3949/ccjm.82a.14105

    Ceftaroline fosamil is the first beta-lactam with clinically useful activity against methicillin-resistant Staphylococcus aureus.

  • The cohabitation of art and genomic science
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine July 2015, 82 (7) 394-395; DOI: https://doi.org/10.3949/ccjm.82b.07015
  • Marijuana is both antiemetic and proemetic
    Marvin Louis Roy Y. Lu, MD and Markus D. Agito, MD
    Cleveland Clinic Journal of Medicine July 2015, 82 (7) 429-434; DOI: https://doi.org/10.3949/ccjm.82a.14023

    Chronic marijuana use can have an emetic effect. Patients shower or bathe in extremely hot water to relieve the symptoms.

  • A continuous cardiac murmur
    Rebecca Napier, MD, Jonathan D. Gardner, MD, Susan Noe, MD, FACC, FACP and Joe B. Calkins, MD, FACC, FACP, FASE
    Cleveland Clinic Journal of Medicine July 2015, 82 (7) 414-418; DOI: https://doi.org/10.3949/ccjm.82a.14068

    A 45-year-old woman presents with progressive shortness of breath and a continuous murmur over the entire precordium.

  • An unusual cause of vitamin B12 and iron deficiency
    Shelley Maithel, BA, Alex K. Duong, Jonathan Zhang, MD and Douglas L. Nguyen, MD
    Cleveland Clinic Journal of Medicine July 2015, 82 (7) 406-408; DOI: https://doi.org/10.3949/ccjm.82a.14151

    Testing for ova and parasites was negative, but video capsule endoscopy revealed a tapeworm in the distal duodenum.

  • Urologic applications of botulinum toxin
    Ashley King, MD, Adrienne Quirouet, MD and Courtenay K. Moore, MD
    Cleveland Clinic Journal of Medicine July 2015, 82 (7) 456-464; DOI: https://doi.org/10.3949/ccjm.82a.13166

    Botulinum toxin is approved for neurogenic detrusor overactivity and overactive bladder refractory to drug therapy.

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