Latest Articles

  • Acute stroke therapy: Beyond IV tPA
    Anthony J. Furlan, MD
    Cleveland Clinic Journal of Medicine September 2002, 69 (9) 730-734;

    The quest to improve treatment includes intra-arterial infusion of thrombolytics, mechanical interventions, and neuroprotection through hypothermia.

  • Follow the evidence—but don’t expect a straight path
    John D. Clough, MD
    Cleveland Clinic Journal of Medicine September 2002, 69 (9) 663;

    The newest data on hormone replacement therapy remind us that evidence-based practice is not cookbook medicine.

  • Choosing the most appropriate valve operation and prosthesis
    Maran Thamilarasan, MD and Brian Griffin, MD
    Cleveland Clinic Journal of Medicine September 2002, 69 (9) 688-703;

    Should the valve be repaired or replaced? And if replaced, which prosthesis is best?

  • Is there a relationship between hypertension and cognitive function in older adults?
    Is there a relationship between hypertension and cognitive function in older adults?
    Rony Abou Jawde, MD and Barbara J. Messinger-Rapport, MD, PhD
    Cleveland Clinic Journal of Medicine September 2002, 69 (9) 664-669;

    Yes, and there is some evidence that treating hypertension protects against cognitive decline later in life.

  • Hormone replacement therapy: Applying the results of the Women’s Health Initiative
    Susan R. Johnson, MD, MS
    Cleveland Clinic Journal of Medicine September 2002, 69 (9) 682-685;

    The ground rules have changed for prescribing hormone replacement therapy. Here are one expert’s recommendations.

  • The ACUTE Trial
    Craig R. Asher, MD and Allan L. Klein, MD
    Cleveland Clinic Journal of Medicine September 2002, 69 (9) 713-718;

    A TEE-guided approach showed no advantage over conventional management in rates of embolic events, but shortened the anticoagulation course, allowed for earlier cardioversion, and caused fewer bleeding events.

  • The crystal, the gout, and the paradox
    Cleveland Clinic Journal of Medicine September 2002, 69 (9) 720;

    We think we know what causes gout, but things may not be so simple.

  • The case for hormone replacement: New studies that should inform the debate
    Holly L. Thacker, MD
    Cleveland Clinic Journal of Medicine September 2002, 69 (9) 670-678;

    Unfortunately, many women who might benefit from hormone replacement may decide to forgo it.

  • Two advances in the management of Parkinson disease
    Two advances in the management of Parkinson disease
    Erwin B. Montgomery, MD
    Cleveland Clinic Journal of Medicine August 2002, 69 (8) 639-643;

    Second-generation dopamine agonists may be preferable to levodopa early in the disease. Deep brain stimulation is remarkably effective in refractory cases.

  • ‘White coat hypertension’—should it be treated or not?
    ‘White coat hypertension’—should it be treated or not?
    Thomas Pickering, MD, DPhil
    Cleveland Clinic Journal of Medicine August 2002, 69 (8) 584-585;

    Treatment is controversial, and any benefit of treatment is unproven.

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