Latest Articles

  • Guide to Clinical Trials ed. by Bert Spilker, PhD, MD
    Rosalie Morss Litt, RN, MPH
    Cleveland Clinic Journal of Medicine September 1992, 59 (5) 553-554;
  • When and Why to Consider Estrogen Therapy
    Delbert L. Booher, MD
    Cleveland Clinic Journal of Medicine July 1992, 59 (4) 345-347;

    Estrogen replacement therapy in postmenopausal women reduces the risk of osteoporosis and cardiovascular disease. Yet only 14% of postmenopausal women who could benefit from estrogen therapy are receiving it.

  • Viral hepatitis in the 1990s, part II: hepatitis B and delta virus
    William D. Carey, MD and Glrish Patel, MD
    Cleveland Clinic Journal of Medicine July 1992, 59 (4) 393-401;

    Effective vaccines are available. High-risk groups have been identified. But widespread prevention of hepatitis B infection remains an elusive goal, and key questions need answers: What are the mechanisms of transmission, including mother-to-offspring transmission? What short - and long-term risks do health care professionals face?

  • Erectile impotence: Goal-Directed Treatment
    Thomas F. Lue, MD
    Cleveland Clinic Journal of Medicine July 1992, 59 (4) 354;
  • Urology update
    David A. Goldfarb, MD
    Cleveland Clinic Journal of Medicine July 1992, 59 (4) 353;
  • Tools for noninvasive assessment of coronary arterial reperfusion
    Richard C. Becker, MD
    Cleveland Clinic Journal of Medicine July 1992, 59 (4) 403-408;

    Coronary angiography has been the standard method to rapidly assess coronary reperfusion status after acute MI, but the availability, cost, and risks of the procedure are potential concerns. Noninvasive markers are showing promise as alternatives to angiography.

  • Primary pulmonary hypertension, then and now: 28 years of experience
    Benjamin D. Robalino, MD and Douglas S. Moodie, MD, MS
    Cleveland Clinic Journal of Medicine July 1992, 59 (4) 411-417;

    Patients with PPH are presenting at earlier stages of the disease, have fewer complications during cardiac catheterization, and probably survive longer after diagnosis than patients seen several decades ago.

  • Prostate cancer: current concepts in diagnosis and treatment
    Eric A. Klein, MD
    Cleveland Clinic Journal of Medicine July 1992, 59 (4) 383-389;

    Controversy persists over how best to screen the general population for prostate cancer, and whether earlier detection decreases mortality. The author outlines an approach to screening, diagnosis, and treatment grounded on A U A guidelines and clinical experience.

  • Diabetic ketoacidosis associated with pheochromocytoma
    Elazer R. Edelman, MD, PhD, Cynthia A. Stuenkel, MD, John D. Rutherford, MB, BCh and Gordon H. Williams, MD
    Cleveland Clinic Journal of Medicine July 1992, 59 (4) 423-427;

    Diabetic ketoacidosis associated with classic findings of pheochromocytoma was seen in a young woman who also had a significant insulin requirement that resolved after excision of the tumor.

  • Doppler echocardiographic assessment of aortic regurgitation: uses and limitations
    Allan L. Klein, MD, Malcolm B. Davison, MBBS, Galen Vonk, MD and A. Jamil Tajik, MD
    Cleveland Clinic Journal of Medicine July 1992, 59 (4) 359-368;

    The final determination of the severity of aortic regurgitation should involve a combination of the various Doppler techniques and the indices derived from them.

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