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Introduction: The transition from milestones to innovations
Maan A. Fares, MD

Cleveland Clinic Journal of Medicine December 2015, 82 (12 suppl 2) S5; DOI: https://doi.org/10.3949/ccjm.82.s2.01
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Clinical challenges in diagnosing and managing adult hypertension
Joel Handler, MD

Cleveland Clinic Journal of Medicine December 2015, 82 (12 suppl 2) S36-S41; DOI: https://doi.org/10.3949/ccjm.82.s2.06
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Biomarkers: Their potential in the diagnosis and treatment of heart failure
Barbara Heil, MD and W. H. Wilson Tang, MD

Cleveland Clinic Journal of Medicine December 2015, 82 (12 suppl 2) S28-S35; DOI: https://doi.org/10.3949/ccjm.82.s2.05
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Stroke management and the impact of mobile stroke treatment units
Peter A. Rasmussen, MD

Cleveland Clinic Journal of Medicine December 2015, 82 (12 suppl 2) S17-S21; DOI: https://doi.org/10.3949/ccjm.82.s2.04
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Evolving strategies to prevent stroke and thromboembolism in nonvalvular atrial fibrillation
Ayman Hussein, MD, Walid Saliba, MD and Oussama Wazni, MD

Cleveland Clinic Journal of Medicine December 2015, 82 (12 suppl 2) S11-S16; DOI: https://doi.org/10.3949/ccjm.82.s2.03
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Should all patients with significant proteinuria take a renin-angiotensin inhibitor?
George Thomas, MD and Joseph V. Nally, MD

Cleveland Clinic Journal of Medicine November 2015, 82 (11) 716-718; DOI: https://doi.org/10.3949/ccjm.82a.15038

Most of them should, with exceptions due to adverse effects such as angioedema, cough, and hyperkalemia.
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Women’s health 2015: An update for the internist
Lisa N. Kransdorf, MD, MPH, Melissa A. McNeil, MD, MPH, Julia A. Files, MD and Marjorie R. Jenkins, MD

Cleveland Clinic Journal of Medicine November 2015, 82 (11) 759-764; DOI: https://doi.org/10.3949/ccjm.82a.15096

Antidepressants in pregnancy, nonhormonal therapies for menopausal symptoms, and heart failure therapy.
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An elderly woman with ‘heart failure’: Cognitive biases and diagnostic error
Nikhil Mull, MD, James B. Reilly, MD, MS and Jennifer S. Myers, MD

Cleveland Clinic Journal of Medicine November 2015, 82 (11) 745-753; DOI: https://doi.org/10.3949/ccjm.82a.14087

The authors review a case to analyze what went wrong and why.
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Pancreas transplant for diabetes mellitus
Hannah R. Kerr, MD, Betul Hatipoglu, MD and Venkatesh Krishnamurthi, MD

Cleveland Clinic Journal of Medicine November 2015, 82 (11) 738-744; DOI: https://doi.org/10.3949/ccjm.82a.14090

Transplant consistently normalizes hemoglobin A1c levels without the risk of severe hypoglycemia.
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The color purple
Abhinav Sood, MBBS, MD, Ashhar Ali, DO and Adarsh Bhimraj, MD

Cleveland Clinic Journal of Medicine November 2015, 82 (11) 721-722; DOI: https://doi.org/10.3949/ccjm.82a.14119

Purple urine bag syndrome is a sign of urinary tract infection and should be treated if symptomatic.

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