Latest Articles

  • ST-segment depression and T-wave inversion: Classification, differential diagnosis, and caveats
    ST-segment depression and T-wave inversion: Classification, differential diagnosis, and caveats
    Elias B. Hanna, MD and David Luke Glancy, MD
    Cleveland Clinic Journal of Medicine June 2011, 78 (6) 404-414; DOI: https://doi.org/10.3949/ccjm.78a.10077

    Knowing the characteristic patterns is critical for a timely diagnosis of life-threatening disorders.

  • Immune thrombocytopenia: No longer ‘idiopathic’
    Keith McCrae, MD
    Cleveland Clinic Journal of Medicine June 2011, 78 (6) 358-373; DOI: https://doi.org/10.3949/ccjm.78gr.10005

    Once regarded as idiopathic, immune thrombocytopenia is now understood to involve both accelerated platelet destruction and impaired platelet production.

  • Facial swelling and ulceration with nasal destruction
    Sudip Kumar Ghosh, MD, DNB, Debabrata Bandyopadhyay, MD and Loknath Ghoshal, MD
    Cleveland Clinic Journal of Medicine May 2011, 78 (5) 289-290; DOI: https://doi.org/10.3949/ccjm.78a.10097

    A 12-year-old boy presents with painless swelling and ulceration on and around his nose. What is the diagnosis?

  • Visceral angioedema due to angiotensin-converting enzyme inhibitor therapy
    Aleksandr Korniyenko, MD, Carlos L. Alviar, MD, Juan P. Cordova, MD and Franz H. Messerli, MD
    Cleveland Clinic Journal of Medicine May 2011, 78 (5) 297-304; DOI: https://doi.org/10.3949/ccjm.78a.10102

    If a middle-aged woman taking an angiotensin-converting enzyme inhibitor presents with abdominal pain and emesis, the differential diagnosis should include this uncommon but serious complication.

  • A practical guide to prostate cancer diagnosis and management
    A practical guide to prostate cancer diagnosis and management
    Matthew N. Simmons, MD, PhD, Ryan K. Berglund, MD and J. Stephen Jones, MD
    Cleveland Clinic Journal of Medicine May 2011, 78 (5) 321-331; DOI: https://doi.org/10.3949/ccjm.78a.10104

    Screening, diagnosis, and management of prostate cancer can be complicated, with no clear consensus about key issues. Our approach refl ects the guidelines from the American Urological Association.

  • Coadministration of clopidogrel and proton pump inhibitors (January 2011)
    David L. Keller, MD
    Cleveland Clinic Journal of Medicine May 2011, 78 (5) 284; DOI: https://doi.org/10.3949/ccjm.78c.05001

    A reader comments on the interaction between clopidogrel (Plavix) and proton pump inhibitors (January 2011).

  • In reply: Coadministration of clopidogrel and proton pump inhibitors (January 2011)
    Ryan D. Madanick, MD
    Cleveland Clinic Journal of Medicine May 2011, 78 (5) 284-285; DOI: https://doi.org/10.3949/ccjm.78c.05002
  • A 46-year-old man with fever, ST-segment elevation
    Atul Singla, MD, Walter Coats, MD and Gregory C. Flaker, MD
    Cleveland Clinic Journal of Medicine May 2011, 78 (5) 286-288; DOI: https://doi.org/10.3949/ccjm.77a.10099

    ST-segment elevation commonly represents acute myocardial infarction, but it is also associated with other conditions.

  • Recognizing the unusual: The diagnostic epiphany
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine May 2011, 78 (5) 277; DOI: https://doi.org/10.3949/ccjm.78b.11005

    We have all experienced the sudden recognition of an unexpected diagnosis, such as the case of visceral angioedema due to angiotensin-converting enzyme therapy reported by Korniyenko et al in this issue of the Journal.

  • Insulin treatment for type 2 diabetes: When to start, which to use
    Marwan Hamaty, MD, MBA
    Cleveland Clinic Journal of Medicine May 2011, 78 (5) 332-342; DOI: https://doi.org/10.3949/ccjm.78a.10051

    Many patients with type 2 diabetes eventually need insulin. This review addresses practical approaches.

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