Latest Articles

  • A 46-year-old man with fever, ST-segment elevation
    Atul Singla, MD, Walter Coats, MD and Gregory C. Flaker, MD
    Cleveland Clinic Journal of Medicine May 2011, 78 (5) 286-288; DOI: https://doi.org/10.3949/ccjm.77a.10099

    ST-segment elevation commonly represents acute myocardial infarction, but it is also associated with other conditions.

  • Recognizing the unusual: The diagnostic epiphany
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine May 2011, 78 (5) 277; DOI: https://doi.org/10.3949/ccjm.78b.11005

    We have all experienced the sudden recognition of an unexpected diagnosis, such as the case of visceral angioedema due to angiotensin-converting enzyme therapy reported by Korniyenko et al in this issue of the Journal.

  • Insulin treatment for type 2 diabetes: When to start, which to use
    Marwan Hamaty, MD, MBA
    Cleveland Clinic Journal of Medicine May 2011, 78 (5) 332-342; DOI: https://doi.org/10.3949/ccjm.78a.10051

    Many patients with type 2 diabetes eventually need insulin. This review addresses practical approaches.

  • Managing newly diagnosed atrial fibrillation: Rate, rhythm, and risk
    Thomas Callahan, MD and Brian Baranowski, MD
    Cleveland Clinic Journal of Medicine April 2011, 78 (4) 258-264; DOI: https://doi.org/10.3949/ccjm.78a.09165

    Treatment focuses on controlling the heart rate, preventing thromboembolic events, and, depending on symptoms, restoring and maintaining sinus rhythm.

  • Gene-based, rational drug-dosing: An evolving, complex opportunity
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine April 2011, 78 (4) 218; DOI: https://doi.org/10.3949/ccjm.78b.11004

    Pharmacogenomics promises the opportunity to match the right drug and dose to the right patient. We are not there yet, but the day is coming.

  • Nausea, vomiting, and panic attacks in a 50-year-old woman
    Joshua Bear, MA and Franklin A. Michota, MD
    Cleveland Clinic Journal of Medicine April 2011, 78 (4) 233-239; DOI: https://doi.org/10.3949/ccjm.78a.10082

    Six months ago she started to have panic attacks that roused her from sleep. Lately, they have become more frequent and more severe. What is the cause?

  • Pharmacogenomics for the primary care provider: Why should we care?
    Kathryn Teng, MD
    Cleveland Clinic Journal of Medicine April 2011, 78 (4) 241-242; DOI: https://doi.org/10.3949/ccjm.78a.11017

    Personalized medicine promises to improve the quality and lower the cost of care if physicians integrate into practice useful new findings, such as information gleaned from pharmacogenomic testing.

  • Ending LGBT invisibility in health care: The first step in ensuring equitable care
    Harvey J. Makadon, MD
    Cleveland Clinic Journal of Medicine April 2011, 78 (4) 220-224; DOI: https://doi.org/10.3949/ccjm.78gr.10006

    Lesbian, gay, bisexual, and transgender individuals experience health care disparities that will be eliminated only if clinicians elicit information in a thoughtful, nonjudgmental way.

  • Leukemia cutis
    Christos Tziotzios, BA, MA, MB, BChir (Cantab) and Areti Makrygeorgou, MD
    Cleveland Clinic Journal of Medicine April 2011, 78 (4) 226-227; DOI: https://doi.org/10.3949/ccjm.78a.10127

    This condition occurs in 10% to 15% of patients with acute myeloid leukemia and is a poor prognostic sign.

  • Pharmacogenomic testing: Relevance in medical practice
    Pharmacogenomic testing: Relevance in medical practice
    Joseph P. Kitzmiller, MD, PhD, David K. Groen, MD, Mitch A. Phelps, PhD and Wolfgang Sadee, Dr rer nat
    Cleveland Clinic Journal of Medicine April 2011, 78 (4) 243-257; DOI: https://doi.org/10.3949/ccjm.78a.10145

    Knowing their patients’ genetic status, physicians could predict their response to certain drugs, such as clopidogrel (Plavix), warfarin (Coumadin), tamoxifen (Nolvadex), codeine, and psychotropic medications.

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