Latest Articles

  • Advances in diagnosing and excluding pulmonary embolism: Spiral CT and D-dimer measurement
    Teresa L. Carman, MD and Steven R. Deitcher, MD
    Cleveland Clinic Journal of Medicine September 2002, 69 (9) 721-729;

    No test is 100% sensitive and specific for pulmonary embolism. The best approach still depends on the pretest probability and, thus, on clinical judgment.

  • Acute stroke therapy: Beyond IV tPA
    Anthony J. Furlan, MD
    Cleveland Clinic Journal of Medicine September 2002, 69 (9) 730-734;

    The quest to improve treatment includes intra-arterial infusion of thrombolytics, mechanical interventions, and neuroprotection through hypothermia.

  • Follow the evidence—but don’t expect a straight path
    John D. Clough, MD
    Cleveland Clinic Journal of Medicine September 2002, 69 (9) 663;

    The newest data on hormone replacement therapy remind us that evidence-based practice is not cookbook medicine.

  • Choosing the most appropriate valve operation and prosthesis
    Maran Thamilarasan, MD and Brian Griffin, MD
    Cleveland Clinic Journal of Medicine September 2002, 69 (9) 688-703;

    Should the valve be repaired or replaced? And if replaced, which prosthesis is best?

  • Is there a relationship between hypertension and cognitive function in older adults?
    Is there a relationship between hypertension and cognitive function in older adults?
    Rony Abou Jawde, MD and Barbara J. Messinger-Rapport, MD, PhD
    Cleveland Clinic Journal of Medicine September 2002, 69 (9) 664-669;

    Yes, and there is some evidence that treating hypertension protects against cognitive decline later in life.

  • Hormone replacement therapy: Applying the results of the Women’s Health Initiative
    Susan R. Johnson, MD, MS
    Cleveland Clinic Journal of Medicine September 2002, 69 (9) 682-685;

    The ground rules have changed for prescribing hormone replacement therapy. Here are one expert’s recommendations.

  • The ACUTE Trial
    Craig R. Asher, MD and Allan L. Klein, MD
    Cleveland Clinic Journal of Medicine September 2002, 69 (9) 713-718;

    A TEE-guided approach showed no advantage over conventional management in rates of embolic events, but shortened the anticoagulation course, allowed for earlier cardioversion, and caused fewer bleeding events.

  • The crystal, the gout, and the paradox
    Cleveland Clinic Journal of Medicine September 2002, 69 (9) 720;

    We think we know what causes gout, but things may not be so simple.

  • Endometriosis: Still tough to diagnose and treat
    Marjan Attaran, MD, Tommaso Falcone, MD and Jeffrey Goldberg, MD
    Cleveland Clinic Journal of Medicine August 2002, 69 (8) 647-653;

    Despite advances, endometriosis is still tough to diagnose, treat, and live with.

  • Progress in preventing chemotherapy-induced nausea and vomiting
    Cleveland Clinic Journal of Medicine August 2002, 69 (8) 609-617;

    Our understanding of the pathophysiology of emesis has improved, and we now have drugs that can prevent acute emesis in most patients. Delayed and anticipatory emesis remain a challenge.

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