Latest Articles
- Accuracy and predictive values in clinical decision-making
The accuracy and predictive value of a diagnostic test may differ substantially between research and clinical populations, owing to differences in disease prevalence. The article suggests ways researchers could end the confusion.
- Asthma: current controversies and emerging therapies
Anti-inflammatory drugs for maintenance therapy, use of beta agonists, emergency management, immunotherapy, and newer therapies.
- Coronary heart disease in African Americans: primary and secondary prevention
How physicians can help improve the cardiovascular health of their black patients, who have a high level of CHD risk factors.
- Pathogenesis of epilepsy: the role of excitatory amino acids
These neurotransmitters seem to play a role in brain development—and also in seizures. Experimental drugs can block their action.
- Chest pain in a patient with congenital heart disease
A self-test featuring a challenging clinical presentation.
- Trends in radiation oncology: a review for the non-oncologist
One hundred years after the first radiation treatment, technical improvements continue, with more-powerful machines and more-precise planning.
- Caring for dying patients: physicians and assisted suicide
Both advocates and opponents can agree on the need for better palliative care.
- Managing acetaminophen overdose
Alcohol and certain drugs potentiate the hepatotoxic effects of this common, over-the-counter analgesic. Treatment with acetylcysteine and, possibly, Cimetidine can prevent irreversible liver damage.