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Cleveland Clinic Journal of Medicine
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Cleveland Clinic Journal of Medicine

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Latest Articles

  • You have access
    All menopausal hormone therapy is not alike
    Henry H. Lindner, MD
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 721-722; DOI: https://doi.org/10.3949/ccjm.92c.12002
  • You have access
    Latent autoimmune diabetes in adults: Not type 1, not type 2, a little of both
    CME article
    Michelle D. Lundholm, MD and Keren Zhou, MD
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 757-763; DOI: https://doi.org/10.3949/ccjm.92a.25069

    Latent autoimmune diabetes in adults shares features of type 1 and type 2 diabetes, often leading to misdiagnosis and a delay in starting needed insulin therapy.

  • You have access
    In reply: All menopausal hormone therapy is not alike
    Samantha F. Butts, MD, MSCE
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 722; DOI: https://doi.org/10.3949/ccjm.92c.12003
  • You have access
    Skin manifestations of mpox
    James Kim, MD, Matt Biondi, MD and Helen Bartels, MB, BChir
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 736-737; DOI: https://doi.org/10.3949/ccjm.92a.25022

    The patient presented with a tender, ulcerated perianal lesion and scattered papules on the trunk and extremities.

  • You have access
    In Reply: Corticosteroids in severe community-acquired pneumonia
    Alejandro Chapa-Rodriguez, MD, Tark Abou-Elmagd, MD, Cody O’Rear, DO and Shraddha Narechania, MD
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 724; DOI: https://doi.org/10.3949/ccjm.92c.12006
  • You have access
    How can I select the right thyroid hormone formulation for my patient with hypothyroidism?
    Lea El Hage, MD and Vinni Makin, MBBS, MD
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 745-747; DOI: https://doi.org/10.3949/ccjm.92a.25042

    Knowing the features of the available thyroid hormone formulations can provide a starting point for individualizing therapy for patients who have concerns about product formulations or remain symptomatic despite a normal thyroid-stimulating hormone level.

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    Managing noninsulin glucose-lowering medications before surgery
    Adam Kaplan, MD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 651; DOI: https://doi.org/10.3949/ccjm.92c.11001
  • You have access
    Lipoprotein ‘little a’: More than a little target in the management of cardiovascular risk?
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 647-648; DOI: https://doi.org/10.3949/ccjm.92b.11025

    Lipoprotein(a) was once believed to play no contributory role in the development of cardiovascular disease. That storyline has since flipped.

  • You have access
    Rethinking recovery in heart failure: Beyond improvement in left ventricular ejection fraction
    Nandan Kodur, BS and W. H. Wilson Tang, MD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 673-675; DOI: https://doi.org/10.3949/ccjm.92a.25078

    The authors discuss 3 unresolved questions about de-escalating and escalating guideline-directed medical therapy in patients with improved ejection fraction.

  • You have access
    Teprotumumab for thyroid eye disease: A reality check
    Julian Perry, MD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 702-703; DOI: https://doi.org/10.3949/ccjm.92a.25066

    Initial enthusiasm for teprotumumab as therapy for thyroid eye disease has been tempered by longitudinal data suggesting that it often does not alter the natural disease course.

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