Latest Articles
- Interpreting the Enhance Trial
The impact of the ENHANCE trial reveals more about the political climate than it does about the effects of ezetimibe on the progression of atherosclerosis.
- A drug, a concept, and a clinical trial on trial
The ENHANCE trial, evaluating the addition of a second hypocholesterolemic drug (ezetimibe) to a statin using two surrogate end points in a relatively small number of patients, hit the national news when the two surrogates didn’t match up.
- Blood smear analysis in babesiosis, ehrlichiosis, relapsing fever, malaria, and Chagas disease
Blood smear analysis should be performed in patients with persistent or recurring fever, those who have traveled to the developing world, or those who have a history of tick exposure, especially if accompanied by hemolytic anemia, thrombocytopenia, or hepatosplenomegaly.