Latest Articles
- Goal-directed antihypertensive therapy: Lower may not always be better
At least 16 trials have been done in which patients were randomly assigned different blood pressure goals. Surprisingly, they did not show that a lower target offered significant clinical benefit, and they suggest the potential for harm.
- Hypertension: Don’t worry about the J curve—treat the patient
Concerns over being too aggressive remain theoretical. A far greater problem is that we are still not successfully treating hypertension to even a conservative target.
- MAO inhibitors (December 2010)
A reader comments on the use of monoamine oxidase inhibitors to treat depression (December 2010) and on the treatment of gout in patients with chronic kidney disease (December 2010).
- Airway pressure release ventilation: An alternative mode of mechanical ventilation in acute respiratory distress syndrome
This mode may be useful in situations in which the lungs need to be recruited (reinflated) and held open.
- A 31-year-old man with abdominal pain and a rectal nodule
He has had pain and diarrhea for 4 days. What is the likely cause?
- Do patients with prosthetic joints require dental antimicrobial prophylaxis?
The authors contend that the available evidence does not support routine prophylaxis before dental procedures.
- Series Introduction
To keep our readers up to date on progress in palliative medicine, we are presenting a series of articles on the topic.
- Managing bloodstream infections in patients who have short-term central venous catheters
Should a potentially infected catheter be removed? Which empiric antibiotic therapy should be started? And how should therapy be tailored to the specific pathogen?