Latest Articles
- Thick skin on the back
An obese woman with long-standing uncontrolled type 2 diabetes mellitus presents with indurated thickening of the skin on her back. What is the diagnosis?
- In Reply: Kidney stones (October 2009)
Readers comment on kidney stones (October 2009) and on fragility fractures in patients with chronic kidney disease (December 2009).
- Consternation and questions about two vertebroplasty trials
Should we abandon this popular procedure? Or are there considerations that may mitigate the negative findings of these two trials?
- Myelodysplastic syndromes: A practical approach to diagnosis and treatment
The myelodysplastic syndromes are clonal bone marrow disorders that lead to underproduction of normal blood cells. Primary care physicians tend to be the first to identify the problem.
- Acetaminophen: Old drug, new warnings
Often, patients overdose because they take more than one acetaminophen product and are unaware that both products contain the drug.
- Lesions on the hands, high aminotransferase levels
A 64-year-old man presents with a 10-day history of painful vesicles and erosions on the dorsa of the hands that appeared after sun exposure. What is the diagnosis?
- Vertebroplasty, cognitive dissonance, and evidence-based medicine: What do we do when the ‘evidence’ says we are wrong?
Two recent trials call into question the efficacy of vertebroplasty for treating osteoporotic vertebral compression fractures and are leading many of us to question our assumptions about vertebroplasty.
- Should we routinely screen for hypercapnia in sleep apnea patients before elective noncardiac surgery?
Yes. Obesity hypoventilation syndrome is often undiagnosed and greatly increases perioperative risk.
- Abdominal pain in a 20-year-old woman
Her body mass index is 18.7, and she has lost 20 lb despite a good appetite. What is the cause?
- Evidence, limes, and cement
Sometimes, the results of clinical trials do not immediately affect what physicians do because the results do not jibe with experience.