Latest Articles
- Myths and facts about Lyme disease
The myth of Lyme disease holds that it is common, protean in its manifestations, and incurable. In reality, Lyme disease is none of these things.
- What's new in the treatment of hypertension
Systolic pressure predicts risk more accurately than diastolic pressure. The current goal of 140/90 is probably not aggressive enough.
- Preoperative evaluation of a woman with rheumatoid arthritis
What testing and action is needed to prepare this patient for evacuation of a hematoma?
- Lipid-lowering therapy for average lipid levels: The CARE trial
The CARE findings indicate that average LDL-cholesterol levels are too high in patients with coronary artery disease and can contribute to a reoccurrence of cardiovascular events.
- Negative-pressure pulmonary edema: a cautionary tale
Acute pulmonary edema due to upper respiratory obstruction (in this case an endotracheal tube obstructed by dry mucus plugs), may be underdiagnosed.
- Treating populations rather than individuals: the subtle danger of managed care
Is managed care improving the quality of health care for populations at the expense of care for individuals?
- From serendipity to design: the evolution of drug development in oncology
Although the screening of natural products remains the major method of discovering new anticancer drugs, new techniques of computer-aided drug design and combinatorial synthesis will also play a role.
- Management of bite wounds and infection in primary care
Bite wounds can be deceptive, as seemingly minor wounds can result in serious complications, such as septic arthritis.
- Disturbing asthma statistics reflect suboptimal management
Beta agonists are used too often and inhaled steroids too little. Leukotrine receptor antagonists will be an important new asthma therapy, but allergy shots remain controversial.
- Beyond statistics: What is really important in medicine?
Clinicians should apply clinical reasoning when interpreting trial results, and researchers should find better ways of measuring “soft” outcomes, such as quality of life.