Latest Articles

  • Carbapenem-resistant Enterobacteriaceae: A menace to our most vulnerable patients
    Federico Perez, MD and David Van Duin, MD, PhD
    Cleveland Clinic Journal of Medicine April 2013, 80 (4) 225-233; DOI: https://doi.org/10.3949/ccjm.80a.12182

    The emergence of carbapenem-resistant Enterobacteriaceae (CRE) highlights the importance of effective antibiotics to maintain the safety of our health care system. Clinicians will encounter CRE as a cause of difficult-to-treat and often fatal infections in hospitalized patients. We review the mechanisms of carbapenem resistance, the dissemination and clinical impact of these resistant organisms, and challenges to their detection, treatment, and control.

  • Options for managing severe aortic stenosis: A case-based review
    Options for managing severe aortic stenosis: A case-based review
    Olcay Aksoy, MD, Bridget L. O’brien, MD, FACC and Venu Menon, MD, FACC, FAHA
    Cleveland Clinic Journal of Medicine April 2013, 80 (4) 243-252; DOI: https://doi.org/10.3949/ccjm.80a.12078

    Today, patients who cannot undergo surgery can be offered a variety of less invasive treatments. We use seven cases to illustrate how to manage these patients.

  • A rapidly growing crusted nodule on the lip
    Paul J. Wirth and Thomas N. Helm, MD
    Cleveland Clinic Journal of Medicine April 2013, 80 (4) 222-224; DOI: https://doi.org/10.3949/ccjm.80a.12050

    The patient, who had a squamous cell carcinoma, underwent Mohs surgery and has done well.

  • Bone mineral density testing: Is a T score enough to determine the screening interval?
    Krupa B. Doshi, MD, CCD, Leila Z. Khan, MD, CCD, Susan E. Williams, MS, MD, CCD and Angelo A. Licata, MD, PhD
    Cleveland Clinic Journal of Medicine April 2013, 80 (4) 234-239; DOI: https://doi.org/10.3949/ccjm.80a.12069

    Although a trial found that women with normal or only slightly low results need not come back for another 15 years, it may not be so simple.

  • Implications of a prominent R wave in V1
    Eric J. Chan, MD, Vijaiganesh Nagarajan, MD, MRCP, FACP and Donald A. Underwood, MD
    Cleveland Clinic Journal of Medicine April 2013, 80 (4) 204-205; DOI: https://doi.org/10.3949/ccjm.80a.11138

    A 19-year-old woman presents with exertional dyspnea. What can her electrocardiogram tell us?

  • Aortic valve replacement: Options, improvements, and costs
    Lars G. Svensson, MD, PhD
    Cleveland Clinic Journal of Medicine April 2013, 80 (4) 253-254; DOI: https://doi.org/10.3949/ccjm.80a.13010

    How aortic valve disease is managed continues to evolve. Issues include outcomes and costs.

  • Introducing two new deputy editors
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine March 2013, 80 (3) 137; DOI: https://doi.org/10.3949/ccjm.80b.03013

    Women’s health expert Pelin Batur, MD and hospitalist James Pile, MD join the Journal staff, replacing Tim Gilligan, MD.

  • Frailty in older adults: Implications for end-of-life care
    Katalin Koller, MD, FRCP and Kenneth Rockwood, MD, FRCPC, FRCP
    Cleveland Clinic Journal of Medicine March 2013, 80 (3) 168-174; DOI: https://doi.org/10.3949/ccjm.80a.12100

    By recognizing and measuring frailty, clinicians can better engage patients and their loved ones in difficult discussions about prognoses and plans, and can ultimately give better palliative care.

  • Bilateral adrenal masses (December 2012)
    Maya Estephan, MD and Justin Moore, MD
    Cleveland Clinic Journal of Medicine March 2013, 80 (3) 186-187; DOI: https://doi.org/10.3949/ccjm.80c.03003

    Readers comment on emergency contraception (November 2012), adrenal masses (December 2012), and the use of statins for primary prevention in women (December 2012).

  • Septic shock: The initial moments and beyond
    Simon W. Lam, PharmD, Seth R. Bauer, PharmD and Jorge A. Guzman, MD
    Cleveland Clinic Journal of Medicine March 2013, 80 (3) 175-184; DOI: https://doi.org/10.3949/ccjm.80a.12002

    Evidence-based protocols have improved the outcomes of septic shock. The authors review the evidence.

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