Latest Articles

  • Unresolved Questions in Breast Cancer Therapy
    G. Thomas Budd, MD, Suzan S. Cheng, MD and Sharon Grundfest, MD
    Cleveland Clinic Journal of Medicine September 1991, 58 (5) 376-377;

    When is radical mastectomy preferable to modified radical mastectomy? Which patients may benefit from chemotherapy, radiotherapy, or hormonal therapy?

  • Headache and hypertension in a 15-year-old
    Ronald J. Lorig, MD, PhD, Kathleen Gleason Beavis, MD, Emmanuel L. Bravo, MD and Robert Kay, MD
    Cleveland Clinic Journal of Medicine September 1991, 58 (5) 379-383;

    A 15-year-old girl with a 4-year history of throbbing occipital headaches presents with hypertension in the range of 180/140 mm Hg.

  • Disorders of platelet function: evaluation and treatment
    Joel S. Bennett, MD
    Cleveland Clinic Journal of Medicine September 1991, 58 (5) 413-417;

    A detailed history provides the best clues to the clinical significance of a bleeding diathesis and is key to selecting appropriate laboratory tests and treatment.

  • Irvine Heinly Page, MD (1901–1991)
    F. Merlin Bumpus, PhD
    Cleveland Clinic Journal of Medicine September 1991, 58 (5) 393;

    The former director of research at the Cleveland Clinic is remembered for his substantial contributions to medicine, especially in the field of hypertension research.

  • Improved Laboratory Diagnosis of Septicemia
    John A. Washington, MD
    Cleveland Clinic Journal of Medicine September 1991, 58 (5) 377;

    Optimal timing of blood cultures and proper skin disinfection are two ways to facilitate the diagnosis.

  • Treating hypertension to prevent coronary disease
    Norman M. Kaplan, MD
    Cleveland Clinic Journal of Medicine September 1991, 58 (5) 432-443;

    Past successes and failures in treating hypertension suggest ways to provide better overall therapy and reduce the incidence of coronary heart disease.

  • Eosinophilia-myalgia syndrome: the Cleveland Clinic experience
    Holly L. Thacker, MD
    Cleveland Clinic Journal of Medicine September 1991, 58 (5) 400-408;

    Significant nerve and muscle involvement, diffuse fasciitis, and weight loss were adverse prognosticating factors in this group of patients. Those who survived the acute phase and stabilized were more likely to continue to improve.

  • Initial studies with FK506 in renal transplantation
    Mark L. Jordan, MD, Ron Shapiro, MD, John Fung, MD, PhD, Andreas Tzakis, MD, Saturo Todo, MD, Shimon Kusne, MD, Jake Demetrius, MD, Thomas R. Hakala, MD and Thomas E. Starzl, MD, PhD
    Cleveland Clinic Journal of Medicine September 1991, 58 (5) 444-446;

    Advantages of this immunosuppressive agent include relatively few side effects and high potency, eliminating the need for steroids in some patients.

  • Managing the hypertensive patient: reasonable goals
    Cleveland Clinic Journal of Medicine September 1991, 58 (5) 431;

    Any approach to treating hypertension should be based on multiple blood pressure readings to establish the diagnosis, aggressive nondrug therapy, and use of low doses when initiating drug therapy.

  • Omeprazole: a new drug for the treatment of acid^peptic diseases
    Gary W. Falk, MD
    Cleveland Clinic Journal of Medicine September 1991, 58 (5) 418-427;

    Gastroesophageal reflux disease, Zollinger-Ellison syndrome, duodenal ulcer, and gastric ulcer are among the disorders that have responded to treatment with this agent—the first of a new class of gastric antisecretory drugs.

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