Latest Articles

  • Omeprazole and clopidogrel: Should clinicians be worried?
    Jeremiah P. Depta, MD and Deepak L. Bhatt, MD, MPH
    Cleveland Clinic Journal of Medicine February 2010, 77 (2) 113-116; DOI: https://doi.org/10.3949/ccjm.77a.09173

    The FDA has warned of a possible interaction between omeprazole (Prilosec) and clopidogrel (Plavix), but for the time being we should not change the way we manage patients.

  • Calcified cysts in the upper abdomen
    Ming-Ju Tsai, MD and Hung-Chun Chen, MD, PhD
    Cleveland Clinic Journal of Medicine February 2010, 77 (2) 96-97; DOI: https://doi.org/10.3949/ccjm.77a.09050

    A plain chest radiograph reveals multiple calcified cysts in the upper abdomen of a man who has been on dialysis for 15 years. What is the most plausible diagnosis?

  • Vertebroplasty, cognitive dissonance, and evidence-based medicine: What do we do when the ‘evidence’ says we are wrong?
    R. Douglas Orr, MD
    Cleveland Clinic Journal of Medicine January 2010, 77 (1) 8-11; DOI: https://doi.org/10.3949/ccjm.77a.09146

    Two recent trials call into question the efficacy of vertebroplasty for treating osteoporotic vertebral compression fractures and are leading many of us to question our assumptions about vertebroplasty.

  • Should we routinely screen for hypercapnia in sleep apnea patients before elective noncardiac surgery?
    Babak Mokhlesi, MD, MSc, Leif Saager, MD and Roop Kaw, MD
    Cleveland Clinic Journal of Medicine January 2010, 77 (1) 60-61; DOI: https://doi.org/10.3949/ccjm.77a.09105

    Yes. Obesity hypoventilation syndrome is often undiagnosed and greatly increases perioperative risk.

  • Abdominal pain in a 20-year-old woman
    Lakshmi S. Pasumarthy, MD, Duane E. Ahlbrandt, MD and James W. Srour, MD
    Cleveland Clinic Journal of Medicine January 2010, 77 (1) 45-50; DOI: https://doi.org/10.3949/ccjm.77a.09067

    Her body mass index is 18.7, and she has lost 20 lb despite a good appetite. What is the cause?

  • Evidence, limes, and cement
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine January 2010, 77 (1) 7; DOI: https://doi.org/10.3949/ccjm/77a.01001

    Sometimes, the results of clinical trials do not immediately affect what physicians do because the results do not jibe with experience.

  • Food allergy and eosinophilic esophagitis: Learning what to avoid
    Sandra Hong, MD and Nicola M. Vogel, MD
    Cleveland Clinic Journal of Medicine January 2010, 77 (1) 51-59; DOI: https://doi.org/10.3949/ccjm.77a.09018

    What we know about the mechanisms of food allergies and eosinophilic esophagitis, how to diagnose them, and how to treat them.

  • Consternation and questions about two vertebroplasty trials
    Marcy B. Bolster, MD
    Cleveland Clinic Journal of Medicine January 2010, 77 (1) 12-16; DOI: https://doi.org/10.3949/ccjm.77a.09161

    Should we abandon this popular procedure? Or are there considerations that may mitigate the negative findings of these two trials?

  • Myelodysplastic syndromes: A practical approach to diagnosis and treatment
    Myelodysplastic syndromes: A practical approach to diagnosis and treatment
    Afsaneh Barzi, MD and Mikkael A. Sekeres, MD, MS
    Cleveland Clinic Journal of Medicine January 2010, 77 (1) 37-44; DOI: https://doi.org/10.3949/ccjm.77a.09069

    The myelodysplastic syndromes are clonal bone marrow disorders that lead to underproduction of normal blood cells. Primary care physicians tend to be the first to identify the problem.

  • Acetaminophen: Old drug, new warnings
    Amy Schilling, PharmD, Rebecca Corey, PharmD, BCPS, Mandy Leonard, PharmD, BCPS and Bijan Eghtesad, MD
    Cleveland Clinic Journal of Medicine January 2010, 77 (1) 19-27; DOI: https://doi.org/10.3949/ccjm.77a.09084

    Often, patients overdose because they take more than one acetaminophen product and are unaware that both products contain the drug.

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