Latest Articles
- Accuracy and predictive values in clinical decision-making
The accuracy and predictive value of a diagnostic test may differ substantially between research and clinical populations, owing to differences in disease prevalence. The article suggests ways researchers could end the confusion.
- Asthma: current controversies and emerging therapies
Anti-inflammatory drugs for maintenance therapy, use of beta agonists, emergency management, immunotherapy, and newer therapies.
- Coronary heart disease in African Americans: primary and secondary prevention
How physicians can help improve the cardiovascular health of their black patients, who have a high level of CHD risk factors.
- Chest pain in a patient with congenital heart disease
A self-test featuring a challenging clinical presentation.
- Trends in radiation oncology: a review for the non-oncologist
One hundred years after the first radiation treatment, technical improvements continue, with more-powerful machines and more-precise planning.
- Caring for dying patients: physicians and assisted suicide
Both advocates and opponents can agree on the need for better palliative care.
- Managing acetaminophen overdose
Alcohol and certain drugs potentiate the hepatotoxic effects of this common, over-the-counter analgesic. Treatment with acetylcysteine and, possibly, Cimetidine can prevent irreversible liver damage.
- Drugs for the prevention and treatment of acute renal failure
Mannitol, loop diuretics, dopamine, and calcium antagonists show promise, but they have not yet been rigorously tested for this indication. Caution is advised.