Coronary insufficiency and 5-fluorouracil therapy: A case report, review, and suggestion regarding mechanism

Donald A. Underwood; Carl W. Groppe; A. Roger Tsai; John Yiannikas; Frederick A. Heupler

Case Report

Coronary insufficiency and 5-fluorouracil therapy

A case report, review, and suggestion regarding mechanism

Donald A. Underwood, M.D., Carl W. Groppe, M.D., A. Roger Tsai, M.D., John Yiannikas, M.D. and Frederick A. Heupler, M.D.

Cleveland Clinic Journal of Medicine March 1983, 50 (1) 29-31;

Donald A. Underwood

1Department of Cardiology

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Carl W. Groppe Jr.

2Department of Hematology and Medical Oncology

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A. Roger Tsai

1Department of Cardiology

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John Yiannikas

1Department of Cardiology

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Frederick A. Heupler Jr.

1Department of Cardiology

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ABSTRACT

This report discusses the clinical and stress electrocardiographic findings in a patient with angina pectoris during courses of cancer chemotherapy with 5-fluorouracil. Similar cases from the literature are reviewed. Coronary artery spasm may be an explanation for the phenomenon.

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Angina pectoris
Chemotherapy
complications
Fluorouracil

Received August 1982.
Accepted September 1982.

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Cleveland Clinic Journal of Medicine

Vol. 50, Issue 1

20 Mar 1983

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Coronary insufficiency and 5-fluorouracil therapy

Donald A. Underwood, Carl W. Groppe, A. Roger Tsai, John Yiannikas, Frederick A. Heupler

Cleveland Clinic Journal of Medicine Mar 1983, 50 (1) 29-31;

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Coronary insufficiency and 5-fluorouracil therapy

Donald A. Underwood, Carl W. Groppe, A. Roger Tsai, John Yiannikas, Frederick A. Heupler

Cleveland Clinic Journal of Medicine Mar 1983, 50 (1) 29-31;

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Keywords

Angina pectoris
Chemotherapy
Complications
Fluorouracil

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Coronary insufficiency and 5-fluorouracil therapy

A case report, review, and suggestion regarding mechanism

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