More articles from Review

  • Experimental therapies for multiple sclerosis: current status
    Donald E. Goodkin, MD, Richard M. Ransohoff, MD and Richard A. Rudick, MD
    Cleveland Clinic Journal of Medicine January 1992, 59 (1) 63-74;

    A critical analysis of current experimental agents and obstacles to the development of effective drug therapy.

  • Experimental limbic epilepsy: models, pathophysiologic concepts, and clinical relevance
    Mohamed Nayel, MD, Issam A. Awad, MD, Mark Larkins, MD and Hans Lüders, MD, PhD
    Cleveland Clinic Journal of Medicine November 1991, 58 (6) 521-530;

    Complex partial seizures originating in the temporal lobe are common in epilepsy patients. Drug treatment is often ineffective. What predisposes a patient to these seizures? How do they occur? Animal studies are providing clues to the puzzle.

  • Initial studies with FK506 in renal transplantation
    Mark L. Jordan, MD, Ron Shapiro, MD, John Fung, MD, PhD, Andreas Tzakis, MD, Saturo Todo, MD, Shimon Kusne, MD, Jake Demetrius, MD, Thomas R. Hakala, MD and Thomas E. Starzl, MD, PhD
    Cleveland Clinic Journal of Medicine September 1991, 58 (5) 444-446;

    Advantages of this immunosuppressive agent include relatively few side effects and high potency, eliminating the need for steroids in some patients.

  • Eosinophilia-myalgia syndrome
    James W. Kazura, MD
    Cleveland Clinic Journal of Medicine May 1991, 58 (3) 257-270;

    What features distinguish EMS from idiopathic hyper-eosinophilic syndrome and helminthic infections such as trichinosis?

  • Strategies for migraine management
    Seymour Diamond, MD
    Cleveland Clinic Journal of Medicine May 1991, 58 (3) 257-261;

    Optimal management of the migraine patient is a matter of time, persistence, and, most important, frequent follow-up.

  • The value of echocardiography in mitral valve repair
    William J. Stewart, MD, Ernesto E. Salcedo, MD and Delos M. Cosgrove, MD
    Cleveland Clinic Journal of Medicine March 1991, 58 (2) 177-183;

    In patients who require surgery for mitral regurgitation, valve repair may offer numerous advantages over valve replacement.

  • Rehabilitation strategies for the complex cardiac patient
    Fredric J. Pashkow, MD
    Cleveland Clinic Journal of Medicine January 1991, 58 (1) 70-75;

    Cardiac rehabilitation is as advantageous for a patient with life-threatening arrhythmias as for the post-coronary bypass patient, but the program should be carefully designed and monitored.

  • Implications of childhood hypercholesterolemia
    Richard E. Garcia, MD and Douglas S. Moodie, MD
    Cleveland Clinic Journal of Medicine November 1990, 57 (8) 715-720;

    Hypercholesterolemia in childhood is a powerful predictor of adult hypercholesterolemia, and is a compelling reason to screen children after, age 3.

  • Oncogenes and cancer: clinical applications
    Andrew J. Fishleder, MD
    Cleveland Clinic Journal of Medicine November 1990, 57 (8) 721-726;

    The identification of genes that play a part in tumor development has significant implications for the diagnosis and treatment of certain neoplasms.

  • Pharmacology and use of headache medications
    Glen D. Solomon, MD
    Cleveland Clinic Journal of Medicine October 1990, 57 (7) 627-635;

    Successful headache treatment depends on correlating the pathophysiology of the disease with drug pharmacology.

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