More articles from Review

  • Sepsis and septic shock: Guideline-based management
    Siddharth Dugar, MD, Chirag Choudhary, MD, MBA and Abhijit Duggal, MD, MPH, MSc, FACP
    Cleveland Clinic Journal of Medicine January 2020, 87 (1) 53-64; DOI: https://doi.org/10.3949/ccjm.87a.18143

    Sepsis requires prompt recognition, appropriate antibiotics, careful hemodynamic support, and control of the source of infection.

  • Sickle cell disease: A primary care update
    Grace Onimoe, MD and Seth Rotz, MD
    Cleveland Clinic Journal of Medicine January 2020, 87 (1) 19-27; DOI: https://doi.org/10.3949/ccjm.87a.18051

    Survival has improved, but patients still face multiorgan damage, chronic anemia, and debilitating pain crises.

  • Beyond depression: Other uses for tricyclic antidepressants
    Joanne Schneider, DNP, RN, CNP, Mary Patterson, CNP and Xavier F. Jimenez, MD, MA
    Cleveland Clinic Journal of Medicine December 2019, 86 (12) 807-814; DOI: https://doi.org/10.3949/ccjm.86a.19005

    The pharmacology of these drugs, their potential uses in conditions other than depression, and safety considerations.

  • Gabapentin for alcohol use disorder: A good option, or cause for concern?
    Vania Modesto-Lowe, MD, MPH, Gregory C. Barron, MD, Benjamin Aronow, BS and Margaret Chaplin, MD
    Cleveland Clinic Journal of Medicine December 2019, 86 (12) 815-823; DOI: https://doi.org/10.3949/ccjm.86a.18128

    There is concern about the potential for abuse. Use it only as a second-line alternative, with caution.

  • Vaping: The new wave of nicotine addiction
    Perry Dinardo, BA and Ellen S. Rome, MD, MPH
    Cleveland Clinic Journal of Medicine December 2019, 86 (12) 789-798; DOI: https://doi.org/10.3949/ccjm.86a.19118

    Despite perceptions that vaping is harmless and claims that it can aid in smoking cessation, risks are emerging.

  • Functional heartburn: An underrecognized cause of PPI-refractory symptoms
    Functional heartburn: An underrecognized cause of PPI-refractory symptoms
    Scott Gabbard, MD and Sonya Vijayvargiya
    Cleveland Clinic Journal of Medicine December 2019, 86 (12) 799-806; DOI: https://doi.org/10.3949/ccjm.86a.19006

    Functional heartburn is the most common cause of failure of proton pump inhibitor therapy.

  • Current management of Barrett esophagus and esophageal adenocarcinoma
    Current management of Barrett esophagus and esophageal adenocarcinoma
    Tavankit Singh, MD, Vedha Sanghi, MD and Prashanthi N. Thota, MD, FACG
    Cleveland Clinic Journal of Medicine November 2019, 86 (11) 724-732; DOI: https://doi.org/10.3949/ccjm.86a.18106

    Risk factors: reflux symptoms > 5 years, male sex, age > 50, white race, central obesity, and smoking.

  • STI update: Testing, treatment, and emerging threats
    Matifadza Hlatshwayo, MD, MPH, Hilary E. L. Reno, MD, PhD and Melanie L. Yarbrough, PhD
    Cleveland Clinic Journal of Medicine November 2019, 86 (11) 733-740; DOI: https://doi.org/10.3949/ccjm.86a.18098

    Fast, sensitive molecular diagnostic tests that use self-collected samples may help bend the upward curve of STIs.

  • SEEDS for success: Lifestyle management in migraine
    Jennifer Robblee, MD, MSc and Amaal J. Starling, MD
    Cleveland Clinic Journal of Medicine November 2019, 86 (11) 741-749; DOI: https://doi.org/10.3949/ccjm.86a.19009

    Lifestyle counseling can be based on the mnemonic SEEDS: sleep, exercise, eat, diary, and stress.

  • Appropriate laboratory testing in Lyme disease
    Appropriate laboratory testing in Lyme disease
    Teny M. John, MD and Alan J. Taege, MD
    Cleveland Clinic Journal of Medicine November 2019, 86 (11) 751-759; DOI: https://doi.org/10.3949/ccjm.86a.19029

    Testing for Lyme disease is challenging and if done incorrectly can lead to unnecessary treatment.

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