Latest Articles
- Unexplained pathology is not always autoimmune
Our success in understanding well-defined autoimmune diseases may make us too willing to attribute yet-unexplained conditions to autoimmunity simply because they share symptoms.
- Surgical de-escalation: Are we ready for ‘observation’ of benign high-risk breast lesions found on core needle biopsy?
Surgical de-escalation is part of a larger movement of de-escalation of multidisciplinary breast cancer treatment. The challenge is to balance oncologic outcomes with surgical morbidity and quality of life.
- A new paradigm for adult ADHD: A focused strategy to monitor treatment
In adults with attention deficit hyperactivity disorder, shifting the focus of treatment from reducing symptoms to increasing task completions can allow the physician and patient to quickly determine effectiveness of pharmacotherapy.
- Celiac disease: Who should I test, and how?
First-degree relatives of patients with celiac disease and patients with dermatitis herpetiformis, type 1 diabetes mellitus, and autoimmune thyroid disease are among those for whom testing is advisable.
- Should urine antigen testing for Legionella pneumophila be ordered for all hospitalized patients with community-acquired pneumonia?
Testing is recommended if the pneumonia is severe, if there has been recent travel, and if there is currently an outbreak of legionnaires disease.
- Finger nodules: Tip of the gouty iceberg
Recurrent, dramatic flares are the cardinal symptom of gouty disease, but some patients exhibit tophi on physical examination or imaging—without flares or pain.
- Guidelines for the management of trigeminal neuralgia
Care pathways for patients with trigeminal neuralgia vary widely. The most recent UK guidelines emphasize the need for evidence-based care plans for multidisciplinary management.
- Eruption of erythema after dieting
During the past 4 weeks, the patient had been increasing his exercise and was on a strict diet for bodybuilding