Latest Articles
- Biochemical markers of bone turnover: Useful but underused
Markers tell us the risk of fracture and are useful in patient management. But will insurance pay for testing?
- Nonalcoholic fatty liver disease: A manifestation of the metabolic syndrome
As we get heavier, our livers get fattier. Despite an explosion of research on nonalcoholic fatty liver disease and gains in understanding its epidemiology and pathogenesis, a number of issues remain unresolved, including how to treat it.
- Preventing renal disease progression: Can complete renin-angiotensin- aldosterone blockade work?
In view of the risks of complete blockade of the renin-angiotensin- aldosterone pathway, more data from clinical trials are needed before the general medical community widely applies this strategy to prevent progressive chronic kidney disease.
- A Clinician and Clinical Trialist’s Perspective
Even though more people died in the intensive-treatment group than in the standard-treatment group, the results from this trial should not substantially alter our usual approach to glucose-lowering.
- A judgment call
A young man hospitalized because of a sickle cell crisis requires a central venous line. However, after the catheter is inserted, an initial chest radiograph reveals that the tip may not be in the right place. What should be done?
Using biochemical markers of bone turnover in clinical practiceAlthough no guidelines to date recommend the widespread use of these markers in clinical practice, we believe they will eventually be accepted.
- When a quick sound bite won’t do
In the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial, why did more patients die if they got intensive therapy than if they got standard therapy? In this issue of the Journal, an investigator in this trial gives his analysis.
- A 51-year-old man with nodular lesions
He presents with a 1-year history of episodic pain, swelling, and stiffness in some of the metacarpophalangeal and proximal interphalangeal joints of his fingers. What is the most likely diagnosis?
- And then there were none? An internist’s reflections
In this issue, Dr. Thomas Lansdale eloquently expresses a common theme: medicine just isn’t that much fun anymore. We’d like to hear some solutions.
- Perioperative statins: More than lipid-lowering?
Soon, the checklist for internists seeing patients about to undergo surgery may include prescribing one of the lipid-lowering drugs called statins.