ABSTRACT
Preliminary data demonstrate that migration, proliferation, and differentiation of prostatic epithelial cells in vitro is altered when the cells are grown on an extracellular matrix rather than on bare plastic. Clonal plating efficiencies are used to distinguish this growth and to identify ways to provide an in vitro model for further study of prostatic carcinogenesis. Consequently, this method, with suggested refinements, may improve the understanding of prostate cancer and related disorders.
- Received December 1983.
- Accepted January 1984.
- Copyright © 1984 The Cleveland Clinic Foundation. All Rights Reserved.