Primary cutaneous B-cell lymphoma

ABSTRACT

B-cell lymphomas may involve the skin late in the course of the disease, but only infrequently have primary presentation in the skin. The cutaneous lesions are red-to-violaceous nodules, most often located on the head and neck. Most patients have been treated with radiation alone or combined with surgical excision of the tumors or systemic chemotherapy. In general, patient survival has been poor. The authors report a case of B-cell lymphoma initially confined to the skin and review the clinical characteristics of these lymphomas as reported in the English-language literature.