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Contributions

Treatment of chronic idiopathic urticaria with astemizole

Christopher J. Huerter, MD, Wilma F. Bergfeld, MD, FACP, William O. Wagner, MD and Jacob W. E. Dijkstra, MD
Cleveland Clinic Journal of Medicine May 1989, 56 (3) 263-266;
Christopher J. Huerter
Department of Dermatology, The Cleveland Clinic Foundation
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Wilma F. Bergfeld
Department of Dermatology, The Cleveland Clinic Foundation
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William O. Wagner
Department of Allergy and Immunology, The Cleveland Clinic Foundation
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Jacob W. E. Dijkstra
Department of Dermatology, The Cleveland Clinic Foundation
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ABSTRACT

Astemizole is anew, long-acting H1 receptor antagonist that has proven effective in controlling the signs and symptoms of chronic idiopathic urticaria, without the sedative and anticholinergic side effects that typify use of many antihistamines. In an eight-week open study of 20 patients, astemizole significantly decreased the signs and symptoms of urticaria, as well as the severity of urticaria by anatomic location. Five patients reported complete clearing. Modest weight gain while on chronic therapy appears to be a significant side effect.

INDEX TERM
  • Urticaria
  • Drug Therapy
  • Received March 1988.
  • Accepted August 1988.
  • Copyright © 1989 The Cleveland Clinic Foundation. All Rights Reserved.
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Cleveland Clinic Journal of Medicine: 56 (3)
Cleveland Clinic Journal of Medicine
Vol. 56, Issue 3
1 May 1989
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Treatment of chronic idiopathic urticaria with astemizole
Christopher J. Huerter, Wilma F. Bergfeld, William O. Wagner, Jacob W. E. Dijkstra
Cleveland Clinic Journal of Medicine May 1989, 56 (3) 263-266;

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Treatment of chronic idiopathic urticaria with astemizole
Christopher J. Huerter, Wilma F. Bergfeld, William O. Wagner, Jacob W. E. Dijkstra
Cleveland Clinic Journal of Medicine May 1989, 56 (3) 263-266;
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  • Urticaria
  • Drug Therapy

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