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Contributions

Perioperative management of 63 patients with pheochromocytoma

Azmy R. Boutros, MB, FF ARCS, FRCP, Emmanuel L. Bravo, MD, Giorgio Zanettin, MD and Ralph A. Straffon, MD
Cleveland Clinic Journal of Medicine October 1990, 57 (7) 613-617;
Azmy R. Boutros
Division of Anesthesiology, The Cleveland Clinic Foundation.
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Emmanuel L. Bravo
The Research Institute, The Cleveland Clinic Foundation.
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Giorgio Zanettin
Division of Anesthesiology, The Cleveland Clinic Foundation.
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Ralph A. Straffon
Department of Urology, The Cleveland Clinic Foundation.
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ABSTRACT

During a 10-year period, 60 patients with confirmed diagnoses of pheochromocytoma underwent a total of 63 surgical procedures. To control extreme blood pressure elevations, 6 patients received phenoxybenzamine preoperatively and 28 patients received prazosin. The remaining 29 patients received neither drug. Intravenous sodium nitroprusside and nitroglycerin, alone or in combination, were used in all but 10 patients to control intraoperative hypertensive episodes. One patient died after surgery due to pre-existing intracranial malignant tumor. All other patients were discharged from the hospital with no clinical evidence of stroke or myocardial infarction. We conclude that pheochromocytoma patients can undergo successful surgery without preoperative profound and long-lasting alpha adrenergic blockade.

INDEX TERM
  • Pheochromocytoma
  • Copyright © 1990 The Cleveland Clinic Foundation. All Rights Reserved.
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Cleveland Clinic Journal of Medicine: 57 (7)
Cleveland Clinic Journal of Medicine
Vol. 57, Issue 7
1 Oct 1990
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Perioperative management of 63 patients with pheochromocytoma
Azmy R. Boutros, Emmanuel L. Bravo, Giorgio Zanettin, Ralph A. Straffon
Cleveland Clinic Journal of Medicine Oct 1990, 57 (7) 613-617;

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Perioperative management of 63 patients with pheochromocytoma
Azmy R. Boutros, Emmanuel L. Bravo, Giorgio Zanettin, Ralph A. Straffon
Cleveland Clinic Journal of Medicine Oct 1990, 57 (7) 613-617;
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