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VanOrdstrand Festschrift

Asthma: current strategies for treatment

Theodore F. Reiss, MD and Muzaffar Ahmad, MD
Cleveland Clinic Journal of Medicine March 1991, 58 (2) 161-169;
Theodore F. Reiss
Department of Pulmonary Medicine, Cleveland Clinic Florida, Ft. Lauderdale, Florida
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Muzaffar Ahmad
Department of Pulmonary Disease, The Cleveland Clinic Foundation, Cleveland, Ohio.
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ABSTRACT

Mortality from asthma is increasing, raising questions about the goals and adequacy of treatment. It is important to understand the pathophysiology of asthma and the rationale and options for treatment. Asthma, a reversible syndrome of airflow obstruction, is not simply spasm of airway smooth muscle; rather, it is a disease characterized by mucosal edema, mucous hypersecretion, and epithelial damage in the airway. Appropriate medical therapy includes treatment with compounds that specifically suppress airway inflammation. The best approach to treatment may be an anti-inflammatory agent—preferably by inhalation—along with an inhaled direct bronchodilator, with objective measures of airflow limitation to assess disease severity.

INDEX TERM
  • Asthma
  • Copyright © 1991 The Cleveland Clinic Foundation. All Rights Reserved.
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Cleveland Clinic Journal of Medicine: 58 (2)
Cleveland Clinic Journal of Medicine
Vol. 58, Issue 2
1 Mar 1991
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Asthma: current strategies for treatment
Theodore F. Reiss, Muzaffar Ahmad
Cleveland Clinic Journal of Medicine Mar 1991, 58 (2) 161-169;

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Asthma: current strategies for treatment
Theodore F. Reiss, Muzaffar Ahmad
Cleveland Clinic Journal of Medicine Mar 1991, 58 (2) 161-169;
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