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Contributions

Stereotactic biopsy of nonneoplastic lesions in adults

Donald M. Whiting, MD, Gene H. Barnett, MD, Melinda L. Estes, MD, Cathy A. Sila, MD, Richard A. Rudick, MD, Samuel J. Hassenbusch, MD, PhD and Charles F. Lanzieri, MD
Cleveland Clinic Journal of Medicine January 1992, 59 (1) 48-55;
Donald M. Whiting
Department of Neurosurgery, The Cleveland Clinic Foundation.
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Gene H. Barnett
Center for Computer Assisted Neurosurgery, The Cleveland Clinic Foundation.
Department of Neurosurgery, The Cleveland Clinic Foundation.
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Melinda L. Estes
Department of Neurology, The Cleveland Clinic Foundation.
Department of, Pathology, The Cleveland Clinic Foundation.
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Cathy A. Sila
Department of Neurology, The Cleveland Clinic Foundation.
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Richard A. Rudick
Department of Neurology, The Cleveland Clinic Foundation.
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Samuel J. Hassenbusch
Department of Neurosurgery, The Cleveland Clinic Foundation.
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Charles F. Lanzieri
Departments of Neuroradiology, The Cleveland Clinic Foundation.
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ABSTRACT

Stereotactic biopsy of intracranial lesions has been used primarily for the diagnosis of neoplastic lesions. A series of 158 consecutive stereotactic biopsies performed at The Cleveland Clinic Foundation resulted in 28 diagnoses of non-neoplastic disorders (18%). The majority of these were infectious, inflammatory, or demyelinating disorders. Stereotactic biopsy alone was diagnostic in 17 cases (61%), and biopsy in conjunction with clinical and laboratory data established definitive diagnoses in six cases (22%). All 23 definitive diagnoses led to modifications in patient management. Permanent neurologic morbidity occurred in only two patients (7%). We maintain that this procedure is underused. Stereotactic biopsy is safe, accurate, and useful for diagnosis of non-neoplastic neurologic disorders when the diagnosis is unclear by conventional means. In such cases, its use can lead to early diagnosis and treatment.

INDEX TERMS
  • Stereotactic Techniques
  • Biopsy
  • Copyright © 1992 The Cleveland Clinic Foundation. All Rights Reserved.
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Cleveland Clinic Journal of Medicine
Vol. 59, Issue 1
1 Jan 1992
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Stereotactic biopsy of nonneoplastic lesions in adults
Donald M. Whiting, Gene H. Barnett, Melinda L. Estes, Cathy A. Sila, Richard A. Rudick, Samuel J. Hassenbusch, Charles F. Lanzieri
Cleveland Clinic Journal of Medicine Jan 1992, 59 (1) 48-55;

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Stereotactic biopsy of nonneoplastic lesions in adults
Donald M. Whiting, Gene H. Barnett, Melinda L. Estes, Cathy A. Sila, Richard A. Rudick, Samuel J. Hassenbusch, Charles F. Lanzieri
Cleveland Clinic Journal of Medicine Jan 1992, 59 (1) 48-55;
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Keywords

  • Stereotactic Techniques
  • Biopsy

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